Pancreatic Necrosis: An Early Finding in Severe Acute Pancreatitis
Pancreatic Necrosis: An Early Finding in Severe Acute Pancreatitis
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胰腺坏死：重症急性胰腺炎的早期发现
DOI：
10.1097/00006676-199305000-00012
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发表时间：
1993
期刊：
影响因子：
2.9
通讯作者：
H. Beger
中科院分区：
文献类型：
--
作者：
R. Isenmann;M. Büchler;W. Uhl;P. Malfertheiner;Markus Martini;H. Beger
尽管胰腺坏死在急性胰腺炎的病程中具有重要的临床意义，但对其何时发展却知之甚少。血清C反应蛋白(CRP)是诊断胰腺坏死的可靠指标，具有较高的诊断率。我们对199例急性胰腺炎患者进行了分析。对45例经CT增强扫描证实为坏死性胰腺炎的患者每日测定血清C反应蛋白，以确定胰腺坏死的发展。所有45例患者均在出现症状的前4天内达到了胰腺坏死的诊断标准。这表明胰腺坏死是一个早期发现，在几个小时内发展。
Despite the clinical importance of pancreatic necrosis in the course of acute pancreatitis, little is known about when it develops. Serum C-reactive protein (CRP) is a reliable parameter with a high detection rate for pancreatic necrosis. We analyzed 199 patients with acute pancreatitis. The development of pancreatic necrosis was ascertained by a daily measurement of serum CRP in 45 patients with contrast-enhanced computed tomographic proven necrotizing pancreatitis. In all 45 cases, the criteria for pancreatic necrosis were satisfied within the first 4 days of the onset of symptoms. This indicates that pancreatic necrosis is an early finding that develops within hours.