Thyroid hormone stimulates the production of insulin-hke growth factor I (IGF-I) by immature rat Sertoli cells
Thyroid hormone stimulates the production of insulin-hke growth factor I (IGF-I) by immature rat Sertoli cells
复制标题
甲状腺激素刺激未成熟大鼠支持细胞产生胰岛素样生长因子 I (IGF-I)
DOI：
10.1016/0303-7207(90)90170-d
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发表时间：
1990
影响因子：
4.1
通讯作者：
E. Fugassa
中科院分区：
文献类型：
--
作者：
S. Palmero;M. Prati;A. Barreca;F. Minuto;G. Giordano;E. Fugassa
The effects of thyroid hormone on insulin-like growth factor I (IGF-I) production by Sertoli cells isolated from immature rats have been investigated. In Sertoli cells from hypothyroid rats the production of IGF-I was significantly lower than in controls and was greatly stimulated by the administration of triiodothyronine (T3) in vivo. The in vitro addition of physiological doses of T3(1 nmol/l) significantly increased the production of IGF-I by cultured Sertoli cells indicating a direct action of the hormone on local IGF-I production. Our results suggest the involvement of IGF-I in the thyroid hormone-dependent maturation of testicular function.
大鼠支持生精细胞共培养物中免疫反应位点和生长调节素-C 的积累。
影响因子：
3.7
作者：
Tres,LL;Smith,EP;VanWyk,JJ;Kierszenbaum,AL
通讯作者：
Kierszenbaum,AL
来自培养的大鼠支持细胞培养基的生长调节素样肽的部分表征。
影响因子：
4.8
作者：
Smith,EP;Svoboda,ME;VanWyk,JJ;Kierszenbaum,AL;Tres,LL
通讯作者：
Tres,LL