EFFECTS OF AGING, SEX, AND PHYSICAL-TRAINING ON CARDIOVASCULAR-RESPONSES TO EXERCISE
EFFECTS OF AGING, SEX, AND PHYSICAL-TRAINING ON CARDIOVASCULAR-RESPONSES TO EXERCISE
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DOI：
10.1161/01.cir.86.2.494
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发表时间：
1992-08-01
期刊：
影响因子：
37.8
通讯作者：
EHSANI, AA
中科院分区：
文献类型：
--
作者：
OGAWA, T;SPINA, RJ;EHSANI, AA
背景最大心率、每搏输出量和氧摄取量的下降以及体重和成分变化对最大摄氧量（VO 2 max）年龄相关性下降的相对贡献尚不清楚，可能受性别和体力活动水平的影响。为了研究年龄、性别和体力活动影响最大摄氧量的机制，我们在次极量和极量跑步机运动中量化了摄氧量、心输出量和心率，并评估了健康的年轻和老年久坐和耐力运动训练的男性和女性的体重和去脂肪质量。对于以毫升每公斤每分钟表示的结果，年龄大三到四十岁与久坐受试者的最大摄氧量降低40-41%和受过训练的受试者的最大摄氧量降低25-32%相关（p
Background. The relative contributions of decreases in maximal heart rate, stroke volume, and oxygen extraction and of changes in body weight and composition to the age-related decline in maximal oxygen uptake (VO2max) are unclear and may be influenced by sex and level of physical activity.Methods and Results. To investigate mechanisms by which aging, sex, and physical activity influence VO2max, we quantified VO2, cardiac output, and heart rate during submaximal and maximal treadmill exercise and assessed weight and fat-free mass in healthy younger and older sedentary and endurance exercise-trained men and women. For results expressed in milliliters per kilogram per minute, a three-to-four-decade greater age was associated with a 40-41% lower VO2max in sedentary subjects and a 25-32% lower VO2max in trained individuals (p