Microfluidic in vivo screen identifies compounds enhancing neuronal regeneration.

Microfluidic in vivo screen identifies compounds enhancing neuronal regeneration.
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微流体体内筛选识别增强神经元再生的化合物。

DOI：
10.1109/iembs.2009.5334771
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发表时间：
2009
期刊：
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
影响因子：
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通讯作者：
Yanik,MehmetFatih
Yanik,MehmetFatih
中科院分区：
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文献类型：
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作者：
Rohde,ChristopherB;Gilleland,Cody;Samara,Chrysanthi;Norton,Stephanie;Haggarty,Stephen;Yanik,MehmetFatih

文献摘要

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化合物筛选是鉴定新的治疗靶点、药物先导和阐明生物过程的基本机制的有力工具。我们在这里报告的结果，第一次在体内小分子筛选化合物增强神经元再生。这些屏幕是由我们开发的微流体设备实现的，
Compound screening is a powerful tool to identify new therapeutic targets, drug leads, and elucidate the fundamental mechanisms of biological processes. We report here the results of the first in vivo small-molecule screens for compounds enhancing neuronal regeneration. These screens are enabled by the microfluidic devices we have developed for