Proteomic dataset of wolframin-deficient mouse heart and skeletal muscles
Proteomic dataset of wolframin-deficient mouse heart and skeletal muscles
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DOI：
10.1016/j.dib.2018.10.015
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发表时间：
2018-12-01
期刊：
影响因子：
1.2
通讯作者：
Koks, Sulev
中科院分区：
文献类型：
--
作者：
Eimre, Margus;Kasvandik, Sergo;Koks, Sulev
本文中呈现的数据与题为“Increased Mitochondrial Protein Levels and Bioenergetics in the musculus rectus femoris of Wfs 1-Deficient mice”的研究文章相关（Eimre et al.，接受出版）。该数据集报告了通过液相色谱/串联质谱法对Wfs 1缺陷小鼠心脏、比目鱼肌和股直肌的白色部分的分析。质谱数据的无标记定量分析鉴定了4056种蛋白质，其中114、212和1290种蛋白质在心脏中差异表达（t检验; p < 0.05）。soleus和M.股直肌，分别在Wfs 1缺陷型和野生型组之间。发现8种蛋白质在所有提到的肌肉中差异表达，其中1种蛋白质在氧化（m.比目鱼肌和心脏）和88骨骼肌。该数据集支持引用的研究，并可用于扩展其他分析。数据可通过ProteomeXchange获得，标识符为PXDO 11019。(C)2018作者爱思唯尔公司出版
The data presented in this article are related to the research article entitled "Increased Mitochondrial Protein Levels and Bioenergetics in the musculus rectus femoris of Wfs1-Deficient mice" (Eimre et al., accepted for publication). This dataset reports the analysis of Wfs1-deficient mouse heart, musculus soleus, and white part of musculus rectus femoris by liquid chromatography/tandem mass spectrometry. Label-free quantitative analysis of the mass spectrometry data identified 4056 proteins, with 114, 212, and 1290 proteins differentially expressed (t-test; p < 0.05) in the heart, m. soleus, and m. rectus femoris, respectively, between the Wfs1-deficient and wild-type groups. Eight proteins were found to be differentially expressed in all mentioned muscles, with 1 protein differently expressed in oxidative (m. soleus and heart) and 88 in skeletal muscles. This dataset supports the cited study and can be used to extend additional analyses. Data are available via ProteomeXchange with identifier PXDO11019. (C) 2018 The Authors. Published by Elsevier Inc.