Curvature-Guided Motility of Microalgae in Geometric Confinement
Curvature-Guided Motility of Microalgae in Geometric Confinement
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DOI：
10.1103/physrevlett.120.068002
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发表时间：
2018-02-07
影响因子：
8.6
通讯作者：
Baeumchen, Oliver
中科院分区：
文献类型：
--
作者：
Ostapenko, Tanya;Schwarzendahl, Fabian Jan;Baeumchen, Oliver
微生物，如细菌和微藻，通常生活在由液相和大量界面组成的栖息地中。这些能动的微生物在其封闭环境中的确切行为方式尚不清楚。利用实验和布朗动力学模拟，我们研究了运动的一个单一的衣原体microchromium在一个孤立的微生境与控制的几何特性。我们演示了如何的几何形状的栖息地控制细胞的导航禁闭。发现细胞在边界附近游动的概率随着壁曲率的增加而增加，如圆形和椭圆形室所见。该理论，利用不对称哑铃模型的细胞和立体壁的相互作用，捕捉这种曲率引导导航定量没有自由参数。
Microorganisms, such as bacteria and microalgae, often live in habitats consisting of a liquid phase and a plethora of interfaces. The precise ways in which these motile microbes behave in their confined environment remain unclear. Using experiments and Brownian dynamics simulations, we study the motility of a single Chlamydomonas microalga in an isolated microhabitat with controlled geometric properties. We demonstrate how the geometry of the habitat controls the cell's navigation in confinement. The probability of finding the cell swimming near the boundary increases with the wall curvature, as seen for both circular and elliptical chambers. The theory, utilizing an asymmetric dumbbell model of the cell and steric wall interactions, captures this curvature-guided navigation quantitatively with no free parameters.