The Brief Adherence Rating Scale (BARS) validated against electronic monitoring in assessing the antipsychotic medication adherence of outpatients with schizophrenia and schizoaffective disorder
The Brief Adherence Rating Scale (BARS) validated against electronic monitoring in assessing the antipsychotic medication adherence of outpatients with schizophrenia and schizoaffective disorder
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DOI：
10.1016/j.schres.2007.12.470
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发表时间：
2008-03-01
影响因子：
4.5
通讯作者：
Rush, A. John
中科院分区：
文献类型：
--
作者：
Byerly, Matthew J.;Nakonezny, Paul A.;Rush, A. John
在精神分裂症门诊患者中，抗精神病药物不依从性很常见，患者及其处方医生严重未发现，并与不良临床结果相关。使用电子监测（EM）作为参考标准，我们评估了一种最近开发的、简短的、铅笔纸的、临床管理的依从性工具[简短依从性评定量表（BARS）]的信度、效度以及灵敏度和特异性，以评估精神分裂症和分裂情感性障碍门诊患者口服抗精神病药物的依从性。在基线和6个月随访时收集61名参与者（n = 35名精神分裂症患者；n = 26名精神分裂情感障碍患者）的EM和BARS依从性和症状严重程度评分。平均BARS与EM依从性之间存在显著正相关(β =0.98; r(s)=0.59, p
Among outpatients with schizophrenia, antipsychotic non-adherence is common, grossly under-detected by patients and their prescribers, and is associated with poor clinical outcomes. Using electronic monitoring (EM) as the reference standard we evaluated the reliability and validity as well as the sensitivity and specificity of a recently developed, brief, pencil-paper, clinician-administered adherence instrument [the Brief Adherence Rating Scale (BARS)] to assess the oral antipsychotic medication adherence of outpatients with schizophrenia and schizoaffective disorder. EM and BARS adherence and symptom severity ratings were gathered at baseline and prospectively at 6 monthly visits in 61 participants (n = 35 with schizophrenia; n = 26 with schizoaffective disorder). A significant positive relationship was found between mean BARS and EM adherence (beta=0.98; r(s)=0.59, p