Material-dependent and material-independent selection processes in the frontal and parietal lobes: an event-related fMRI investigation of response competition
Material-dependent and material-independent selection processes in the frontal and parietal lobes: an event-related fMRI investigation of response competition
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DOI：
10.1016/s0028-3932(03)00040-x
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发表时间：
2003-01-01
期刊：
影响因子：
2.6
通讯作者：
Gabrieli, JDE
中科院分区：
文献类型：
--
作者：
Hazeltine, E;Bunge, SA;Gabrieli, JDE
本研究使用侧翼任务[Percept.心理学。16（1974）143]来识别支持响应选择过程的神经结构，并确定这些结构中的哪些结构根据与响应相关联的刺激材料的类型而不同地响应。参与者在进行事件相关功能性磁共振成像（fMRI）时执行了两个版本的侧翼任务。两个版本的任务都要求参与者对中央刺激做出反应，而不管与同时呈现的侧翼刺激相关的反应，但是一个使用彩色圆圈刺激，另一个使用字母刺激。通过比较不一致试验（其中侧翼刺激指示与中央刺激不同的反应）与中性刺激（其中侧翼刺激指示无反应）来确定竞争相关激活。右额下回内的区域表现出显着更多的竞争相关激活的颜色刺激，而两个半球的额中回内的区域表现出更多的竞争相关激活的字母刺激。竞争两种刺激材料均能显著激活右侧额中回和额下回的边缘以及前扣带回（ACC）。后部病灶表现出类似的模式：左下顶叶皮层表现出更大的竞争相关的激活的字母，而右顶叶皮层显着激活的竞争两种材料。这些研究结果表明，响应竞争的决议调用材料依赖和材料独立的过程。出版社：Elsevier Science Ltd
The present study used the flanker task [Percept. Psychophys. 16 (1974) 143] to identify neural structures that support response selection processes, and to determine which of these structures respond differently depending on the type of stimulus material associated with the response. Participants performed two versions of the flanker task while undergoing event-related functional magnetic resonance imaging (fMRI). Both versions of the task required participants to respond to a central stimulus regardless of the responses associated with simultaneously presented flanking stimuli, but one used colored circle stimuli and the other used letter stimuli. Competition-related activation was identified by comparing Incongruent trials, in which the flanker stimuli indicated a different response than the central stimulus, to Neutral stimuli, in which the flanker stimuli indicated no response. A region within the right inferior frontal gyrus exhibited significantly more competition-related activation for the color stimuli, whereas regions within the middle frontal gyri of both hemispheres exhibited more competition-related activation for the letter stimuli. The border of the right middle frontal and inferior frontal gyri and the anterior cingulate cortex (ACC) were significantly activated by competition for both types of stimulus materials. Posterior foci demonstrated a similar pattern: left inferior parietal cortex showed greater competition-related activation for the letters, whereas right parietal cortex was significantly activated by competition for both materials. These findings indicate that the resolution of response competition invokes both material-dependent and material-independent processes. Published by Elsevier Science Ltd.