Heart rate variability: Sleep stage, time of night, and arousal influences
Heart rate variability: Sleep stage, time of night, and arousal influences
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DOI：
10.1016/s0921-884x(96)96070-1
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发表时间：
1997-05-01
期刊：
影响因子：
--
通讯作者：
Arand, DL
中科院分区：
文献类型：
--
作者：
Bonnet, MH;Arand, DL
频谱分析被用来评估心率变异性在连续5分钟的时期在夜间在12个正常成人。同时时间编码的EEC和数字化EKG允许检查心率变异性作为睡眠阶段的函数，夜间时间和EEG唤醒的存在。结果重复了先前的研究，显示在NREM睡眠阶段心率变异性的高频成分增加，低频成分减少，而REM睡眠和觉醒的变化相反。这些结果与REM睡眠和清醒期间的交感神经系统激活一致。在REM睡眠期间观察到的心率变异性的变化开始于NREM睡眠中，比标准的REM评分早几分钟，并且通常持续到REM睡眠结束之后。在阶段2和相同程度的REM睡眠期间的EEG唤醒也与心率变异性的变化相关，这与交感神经激活一致。在EEG唤醒附近的心跳到心跳间隔的检查显示在EEG唤醒之前至少10次心跳的心率加速。觉醒数据沿着阶段2睡眠过渡数据支持以下论点：中枢神经系统交感神经活动的增加先于REM睡眠和睡眠期间觉醒的开始，并可能在REM睡眠和睡眠期间觉醒的开始中起作用。(C)1997 Elsevier Science爱尔兰有限公司
Spectral analysis was used to assess heart rate variability in consecutive 5-min epochs during the night in 12 normal adults. Simultaneous time coding of EEC and digitized EKG allowed examination of heart rate variability as a function of sleep stage, time of night and presence of EEG arousal. The results replicated previous studies in showing increases in high frequency components and decreases in low frequency components of heart rate variability across NREM sleep stages and opposite changes in REM sleep and wake. These results are consistent with sympathetic nervous system activation during REM sleep and wake periods. The shift in heart rate variability seen during REM sleep began in NREM sleep several minutes prior to standardly scored REM and often continued beyond the end of REM sleep. EEG arousals during Stage 2 and to same extent REM sleep were also associated with changes in heart rate variability which were consistent with sympathetic activation, hn examination of beat to beat intervals in proximity to EEG arousals showed heart rate acceleration at least 10 beats prior to the EEG arousal. The arousal data along with Stage 2 sleep transition data support the contention that increases in central nervous system sympathetic activity precede and possibly play a role in the initiation of REM sleep and arousals during sleep. (C) 1997 Elsevier Science Ireland Ltd.