Electrochemical properties of estradiol at glassy carbon electrode modified with nano-Al2O3 film
Electrochemical properties of estradiol at glassy carbon electrode modified with nano-Al2O3 film
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DOI：
10.1016/s0928-4931(03)00053-5
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发表时间：
2003-10
期刊：
影响因子：
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通讯作者：
Qiong He;Shuai Yuan;Cui Chen;Shengshui Hu
中科院分区：
文献类型：
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作者：
Qiong He;Shuai Yuan;Cui Chen;Shengshui Hu
将纳米Al_2O_3分散在玻碳电极（GCE）表面。这种纳米结构膜修饰的GCE对雌二醇（E2）的氧化表现出极大的增强作用，尤其是当样品溶液中加入足够浓度的阳离子表面活性剂（例如十六烷基三甲基溴化铵（CTAB））时。由于纳米粒子的独特性质及其与某些双分子基团选择性联合收割机结合的倾向，以及E2和CTAB在电极表面的协同吸附，E2的伏安响应比没有CTAB的裸GCE更灵敏。E2的最低可检测浓度（3σ）估计为8×10 - 8 mol l-1（积累2 min）。峰电流与E2浓度在4×10 - 7-4×10 - 5 moll-1范围内呈线性关系（R=0.9932）。用线性扫描伏安法和循环伏安法研究了E2在该修饰电极上的电化学性质。利用扫描电镜（SEM）和BET对纳米Al 2 O3膜修饰电极的表面进行了表征。
Nano-Al2O3is dispersed onto the surface of the glassy carbon electrode (GCE). This nanostructured film modified GCE exhibits a great enhancement to the oxidation of estradiol (E2), especially when adequate concentration of cationic surfactant such as cetyltrimethylammonium bromide (CTAB) is added into the sample solution. Due to the nanoparticle's unique properties and its inclination to selectively combine with some groups of bimolecules, as well as synergistic adsorption of E2and CTAB on the electrode surface, E2gives a more sensitive voltammetric response compared with bare GCE performed in the absence of CTAB. The lowest detectable concentration (3σ) of E2is estimated to be 8×10−8mol l−1(accumulation for 2 min). The linear relationship between peak current and concentration of E2holds in the range 4×10−7–4×10−5mol l−1(R=0.9932). The electrochemical properties of E2on this modified electrode are investigated by linear scan voltammetry and cyclic voltammetry. Scanning electron microscope (SEM) and BET are employed to characterize the surface of the electrode modified with nano-Al2O3film.