A molecular link between the sudden infant death syndrome and the long-QT syndrome.

A molecular link between the sudden infant death syndrome and the long-QT syndrome.
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DOI:
10.1056/nejm200007273430405
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发表时间:
2000-07-27
影响因子:
158.5
通讯作者:
Bloise, R
Bloise, R
中科院分区:
医学1区
文献类型:
--
作者:
Schwartz, PJ;Priori, SG;Bloise, R

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婴儿猝死综合症仍然是婴儿出生后第一年死亡的主要原因,对受影响的家庭具有毁灭性的影响。1 - 4尽管有许多假设,3、4婴儿猝死综合症的原因仍然不确定;因此,建议的唯一预防措施是避免婴儿以俯卧姿势睡觉。5 1998年,我们报告了一项为期19年的前瞻性研究的结果,研究对象为34,000多名在出生后第三天或第四天接受心电图检查的婴儿。
The sudden infant death syndrome (SIDS) remains the leading cause of death in the first year of life and has a devastating impact on the affected families.1–4Despite the fact that there have been many hypotheses,3,4the cause or causes of SIDS are still uncertain; as a consequence, the only preventive measure recommended is to avoid having infants sleep in a prone position.5In 1998, we reported the results of a 19-year prospective study of more than 34,000 infants who underwent electrocardiography on the third or fourth day of life.6We tested the hypothesis7,8that the congenital . . .