Microstructure and antibacterial efficacy of graphene oxide nanocomposite fibres
Microstructure and antibacterial efficacy of graphene oxide nanocomposite fibres
复制标题
DOI：
10.1016/j.jcis.2020.03.037
复制
发表时间：
2020-07-01
影响因子：
9.9
通讯作者：
Edirisinghe, Mohan
中科院分区：
文献类型：
--
作者：
Matharu, Rupy Kaur;Tabish, Tanveer A.;Edirisinghe, Mohan
采用加压旋转法制备了含氧化石墨烯纳米片的抗菌聚合物纳米复合纤维网。利用扫描电镜（SEM）、拉曼光谱（Raman spectroscopy）、拉曼映射（Raman mapping）和傅里叶变换红外光谱（FT-IR）对所得纤维网的形态和化学成分进行了测定。扫描电镜显示，随着氧化石墨烯负载的增加，纤维的平均直径从类似的1-4 μ m增加。FT-IR和拉曼光谱证实了氧化石墨烯纳米片在纤维表面的包裹。利用大肠杆菌K12研究了氧化石墨烯纳米复合纤维的抗菌潜力。平均细菌减量范围为46%至85%，结果表明含有8 wt%氧化石墨烯的纳米复合材料具有最强的生物活性。最后，通过活性氧（ROS）的形成来评价纳米复合材料的细菌毒性。提出了纳米复合纤维抗菌性能的机理。抗菌研究后纤维的受激发拉曼散射成像和光谱显示，氧化石墨烯薄片分布在聚2-甲基丙烯酸甲酯（PMMA）纤维的表面，这有助于复合材料对大肠杆菌的高杀灭效果。嵌入在聚合物基体中的氧化石墨烯纳米片已经证明了保持其抗菌性能的能力，从而使其成为一种有前途的抗菌剂。(C) 2020爱思唯尔公司版权所有。
Antibacterial polymer nanocomposite fibre meshes containing graphene oxide (GO) nanosheets were successfully prepared by pressurised gyration. The morphological and chemical composition of the resulting fibre meshes were determined using Scanning Electron Microscopy (SEM), Raman spectroscopy, Raman mapping and Fourier-Transform Infrared Spectroscopy (FT-IR). SEM showed the fibres to have an average diameter increasing from similar to 1-4 mu m as the GO loading increased. FT-IR and Raman spectroscopy confirmed the inclusion of GO nanosheets on the fibre surface. The antibacterial potential of GO nanocomposite fibres were investigated using Escherichia coli K12. Average bacterial reduction ranged from 46 to 85 % with results favouring the strongest bioactivities of the nanocomposite containing 8 wt% of GO. Finally, bacterial toxicity of the nanocomposites was evaluated by reactive oxygen species (ROS) formation. A mechanism for the antibacterial behaviour of the nanocomposite fibres is presented. Stimulated Raman scattering imaging and spectra of the fibres post antibacterial studies showed flakes of GO distributed across the surface of the poly(methyl 2-methylpropenoate) (PMMA) fibres, which contribute to the high killing efficacy of the composites towards E. coli. GO nanosheets embedded in a polymer matrix have demonstrated the ability to retain their antibacterial properties, thus offering themselves as a promising antibacterial agent. (C) 2020 Elsevier Inc. All rights reserved.