Sustained effects of pleasant and unpleasant smells on resting state brain activity
Sustained effects of pleasant and unpleasant smells on resting state brain activity
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DOI：
10.1016/j.cortex.2020.06.017
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发表时间：
2020-11-01
期刊：
影响因子：
3.6
通讯作者：
Vuilleumier, Patrik
中科院分区：
文献类型：
--
作者：
Carlson, Heather;Leitao, Joana;Vuilleumier, Patrik
研究表明，短暂的情绪发作在随后的休息状态下对心理功能和大脑活动产生持续影响。在这项功能磁共振成像研究中，我们调查了由气味引起的短暂情绪是否会以特定的方式影响休息时的大脑连接。研究结果表明，默认模式网络的部分持续重新配置，这些部分与嗅觉处理、情绪学习和动作控制相关的区域联系更加紧密。我们发现气味剂对随后的静息状态的挥之不去的影响，主要涉及楔前叶与包括杏仁核，杏仁核，内侧眶回的网络的连接。令人不快的气味尤其预示着脑岛、海马结构和前额叶皮质之间的耦合更大，这可能反映了厌恶学习和回避动机的增强。更广泛地说，我们的研究说明了一种新的方法来描述气味对大脑功能的影响，并在无任务的休息条件下区分其效价的神经特征。(C)2020作者（S）爱思唯尔有限公司出版
Research suggests that transient emotional episodes produces sustained effects on psychological functions and brain activity during subsequent resting state. In this fMRI study we investigated whether transient emotions induced by smells could impact brain connectivity at rest in a valence-specific manner. The results suggest a sustained reconfiguration of parts of the default mode network which become more connected with areas implicated in olfactory processing, emotional learning, and action control. We found lingering effects of odorants on subsequent resting state that predominantly involved connections of the precuneus with a network comprising the insula, amygdala, medial orbital gyrus. Unpleasant smells in particular predicted greater coupling between insula, hippocampal structures, and prefrontal cortex, possible reflecting enhanced aversive learning and avoidance motivation. More broadly, our study illustrates a novel approach to characterize the impact of smells on brain function and differentiate the neural signatures of their valence, during task-free rest conditions. (C) 2020 The Author(s). Published by Elsevier Ltd.