Human sclera: Thickness and surface area

Human sclera: Thickness and surface area
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DOI:
10.1016/s0002-9394(99)80096-8
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发表时间:
1998-02-01
影响因子:
4.2
通讯作者:
Edelhauser, HF
Edelhauser, HF
中科院分区:
医学1区
文献类型:
--
作者:
Olsen, TW;Aaberg, SY;Edelhauser, HF

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目得:方法:55只福尔马林固定眼库眼,从前向后半切,测量巩膜的平均厚度和表面积。拍摄横截面幻灯片,每张照片中包括毫米刻度尺。投影幻灯片照片并勾画巩膜轮廓。获得平均巩膜厚度测量值和标准差。25只眼库眼被用来确定总巩膜表面积的计算机跟踪方法,(17个球体)或体积计算(八个球)使用流体置换。角巩膜利姆布斯处的平均巩膜厚度+/- SD为0.53 +/- 0.14 mm,赤道附近显著降低至0.39 +/- 0.17 mm,在视神经附近增加到0.9 ~ 1.0mm。表面积计算机描记法测得的平均总巩膜表面积为16.3 +/- 1.8 cm(2),体积置换法测得的平均总巩膜表面积为17.0 +/- 1.5 cm(2)。结论:尸体眼的巩膜厚度和表面积测量对眼科医生很重要,并对经巩膜扩散有影响。
PURPOSE: To assess the mean thickness and surface area of human sclera.METHODS: Fifty-five formalin-fixed eye bank eyes were hemisected from anterior to posterior. Cross;sectional slides were taken to include a millimeter scale ruler in each photograph. Slide photographs were projected and the scleral silhouette sketched. Mean scleral thickness measurements with standard deviation were obtained. Twenty-five human eye bank eyes were used to determine total scleral surface area by either a computerized tracing method (17 globes) or volumetric calculations (eight globes) using fluid displacement.RESULTS: Mean scleral thickness +/- SD was 0.53 +/- 0.14 mm at the corneoscleral limbus, significantly decreasing to 0.39 +/- 0.17 mm near the equator, and increasing to 0.9 to 1.0 mm near the optic nerve. The mean total scleral surface area by surface area computerized tracings was 16.3 +/- 1.8 cm(2) and, by the volume displacement method, was 17.0 +/- 1.5 cm(2).CONCLUSIONS: Scleral thickness and surface area measurements from cadaver eyes are important for ophthalmic surgeons and have implications for transscleral diffusion.