Validation of the Patient Global Impression of Improvement (PGI-I) for urogenital prolapse
Validation of the Patient Global Impression of Improvement (PGI-I) for urogenital prolapse
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DOI：
10.1007/s00192-009-1069-5
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发表时间：
2010-05-01
影响因子：
1.8
通讯作者：
Cardozo, Linda
中科院分区：
文献类型：
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作者：
Srikrishna, Sushma;Robinson, Dudley;Cardozo, Linda
目前，在脱垂研究中没有全球性的结局评估指标。患者总体改善印象（PGI-I）仅在尿失禁中得到验证。我们的目的是验证其在脱垂手术后的应用，从等待名单中招募脱垂妇女并进行客观评估（盆腔器官脱垂量化系统（POP-Q））。采用脱垂生活质量问卷（pQoL）评估生活质量（QoL）。患者目标实现（视觉模拟量表（VAS））确定主观满意度，PGI-I表示总体满意度。我们通过将最终PGI-I反应与1年时测量的其他反应指标相关联，建立了PGI-I的结构效度：（POP-Q/pQoL/VAS）PGI-I与其他结果指标之间有极好的重测信度和相关性。我们相信这是第一项验证PGI-I作为脱垂手术反应的全球指标的研究。这可能是一个有价值的补充，不仅在临床实践中，而且在比较手术干预的试验。
Currently, there is no global outcome assessment index in prolapse research. Patient Global Impression of Improvement (PGI-I) has only been validated in incontinence. Our aim was to validate its use following prolapse surgery.Women with prolapse were recruited from waiting lists and assessed objectively (pelvic organ prolapse quantification system (POP-Q)). Quality of life (QoL) was assessed with prolapse QoL questionnaire (pQoL). Patient goal achievement (visual analogue scale (VAS)) determined subjective satisfaction and PGI-I indicated overall satisfaction. We established construct validity of PGI-I by correlating final PGI-I response with other measures of response, measured at 1 year: (POP-Q/pQoL/VAS)There was excellent test-retest reliability and correlation between PGI-I and other outcome measures.We believe this is the first study validating PGI-I as a global index of response to prolapse surgery. This may be a valuable addition not only in clinical practice but also in trials comparing surgical interventions.