Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial

Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial
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DOI:
10.1016/j.ijid.2007.04.001
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发表时间:
2007-07-01
影响因子:
8.4
通讯作者:
Morrison, W. Ivan
Morrison, W. Ivan
中科院分区:
医学2区
文献类型:
--
作者:
Donnelly, Christl A.;Wei, Gao;Morrison, W. Ivan

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背景:牛结核病(TB)再次成为英国养牛农民的主要问题。未能控制感染与欧洲獾的传播有关;因此,自1973年以来,獾切割已成为英国结核病控制政策的一个组成部分。为了调查重复广泛的獾切割对牛结核病的影响,随机獾切割试验比较了10个切割区及其附近牛群的结核病发病率结果:牛结核病发病率在扑杀区为23.2%(95%CI为12.4-32.7%),在陆地上为24.5%(95%CI为0.6%~ 56.0
Background: Bovine tuberculosis (TB) has re-emerged as a major problem for British cattle farmers. Failure to control the infection has been linked to transmission from European badgers; badger cutting has therefore formed a component of British TB control policy since 1973.Objectives and design: To investigate the impact of repeated widespread badger cutting on cattle TB, the Randomised Badger Cutting Trial compared TB incidence in cattle herds in and around ten cutting areas (each 100 km(2)) with those in and around ten matched unculled areas.Results: Overall, cattle TB incidence was 23.2% tower (95% confidence interval (Cl) 12.4-32.7% tower) inside culled areas, but 24.5% (95% Cl 0.6% lower-56.0% higher) higher on land