Sono-activated ultrasound localization microscopy
Sono-activated ultrasound localization microscopy
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DOI：
10.1063/1.4826597
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发表时间：
2013-10-21
影响因子：
4
通讯作者：
Tanter, Mickael
中科院分区：
文献类型：
--
作者：
Desailly, Yann;Couture, Olivier;Tanter, Mickael
Scanned at very high ultrasound frame rates, injectable microbubbles can be activated sequentially as isolated punctual sources of acoustic echoes. These signals can thus be localized far beyond the diffraction limit. The resolution improvement granted by Sono-Activated Ultrasound Localization Microscopy (SAULM) was demonstrated within microfluidic channels 20 times smaller than the imaging wavelength (lambda = 870 mu m). The width of the channels mapped with SAULM was 13 times smaller than as they appeared under conventional ultrasound imaging. Two channels separated by lambda/4.5 could be distinguished. Implementing SAULM in-vivo could lead to a complete reconstruction of the vascular tree down to the smallest capillaries at several centimeter depth. (C) 2013 AIP Publishing LLC.
