Using inverse Laplace transform in positronium lifetime imaging
Using inverse Laplace transform in positronium lifetime imaging
复制标题
在正电子寿命成像中使用拉普拉斯逆变换
DOI:
10.1088/1361-6560/ac499b
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发表时间:
2022
期刊:
影响因子:
--
通讯作者:
Yamaya Taiga
中科院分区:
文献类型:
--
作者:
Shibuya Kengo;Saito Haruo;Tashima Hideaki;Yamaya Taiga
Positronium (Ps) lifetime imaging is gaining attention to bring out additional biomedical information from positron emission tomography (PET). The lifetime of Ps in vivo can change depending on the physical and chemical environments related to some diseases. Due to the limited sensitivity, Ps lifetime imaging may require merging some voxels for statistical accuracy. This paper presents a method for separating the lifetime components in the voxel to avoid information loss due to averaging. The mathematics for this separation is the inverse Laplace transform (ILT), and the authors examined an iterative numerical ILT algorithm using Tikhonov regularization, namely CONTIN, to discriminate a small lifetime difference due to oxygen saturation. The separability makes it possible to merge voxels without missing critical information on whether they contain abnormally long or short lifetime components. The authors conclude that ILT can compensate for the weaknesses of Ps lifetime imaging and extract the maximum amount of information.
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影响因子:
--
作者:
R. A. Ferrell
通讯作者:
R. A. Ferrell
影响因子:
1.6
作者:
M. Alkhorayef;E. Abuelhia;M. Chin;N. Spyrou
通讯作者:
N. Spyrou
DOI:
10.1088/1742-6596/443/1/012003
发表时间:
2013-06
期刊:
Journal of Physics: Conference Series
影响因子:
--
作者:
K. Wada;T. Hyodo
通讯作者:
K. Wada;T. Hyodo
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
K. Shibuya;Y. Kawamura;H. Saito
通讯作者:
H. Saito
DOI:
--
发表时间:
2007
期刊:
Phys. Med. Biol 52, (1)
影响因子:
--
作者:
Shibuya;K.;Yoshida;E.;Nishikido;F.;Suzuki;T.;Tuda;T.;Inadama;N.;Yamaya;T.;Murayama;H
通讯作者:
H