Perceived self-control of seizures in patients with uncontrolled partial epilepsy
Perceived self-control of seizures in patients with uncontrolled partial epilepsy
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DOI：
10.1016/j.seizure.2004.11.002
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发表时间：
2005-03-01
影响因子：
3
通讯作者：
No, YJ
中科院分区：
文献类型：
--
作者：
Lee, SA;No, YJ
许多癫痫患者在癫痫发作前有警告症状，其中一些人报告有中止或预防癫痫发作的能力。我们调查了感知自我控制的临床特征。174例不受控制的部分性癫痫。根据预警事件与随后的癫痫发作之间的关系，将预警症状分为先兆（前驱症状）和单纯部分性癫痫发作的初始症状。约50%的单纯性部分性癫痫发作患者和约70%的前驱症状或先兆症状患者报告，他们可以通过各种自行开发的技术中止或预防癫痫发作。试图流产或预防癫痫发作的患者报告成功率高达80%。试图中止癫痫发作的患者继发全身性癫痫发作的比例明显低于未尝试中止癫痫发作的患者（p < 0.05）。MRI显示有脑病变患者预防癫痫发作的能力明显高于无脑病变患者（p < 0.05）。这些结果表明，自发发展的方法有助于控制一些不受控制的部分癫痫患者的癫痫发作，并且自我控制方法的潜在成功可能受到脑MRI结构异常的影响。(C) 2004东亚贸易有限公司Elsevier Ltd.出版。版权所有。
Many patients with epilepsy have warning symptoms prior to seizure onset, and some of these individuals report the ability to abort or prevent these seizures. We investigated the clinical characteristics of perceived self-control. of seizures in 174 patients with uncontrolled partial epilepsy. The warning symptoms were categorized as premonitory (prodrome) and as initial symptoms of simple partial seizure onset, depending on the relationship between the warning events and the ensuing seizures. About 50% of the patients with simple partial seizure onset and about 70% of those with prodrome or premonitory symptoms reported that they could abort or prevent their seizures by various self-developed techniques. Patients who attempted to abort or prevent their seizures reported success rates as high as 80%. The proportion of patients with secondary generalized seizures was significantly Lower in patients who tried to abort their seizures than in those who did not (p < 0.05). The ability to prevent seizures was significantly higher in patients with brain Lesions on MRI than in those without Lesions (p < 0.05). These results suggest that spontaneously developed methods are helpful in controlling seizures in some patients with uncontrolled partial epilepsy and that the potential success of self-control methods may be influenced by structural abnormalities on brain MRI. (C) 2004 BEA Trading Ltd. Published by Elsevier Ltd. All rights reserved.