Positron emission tomography in dementia of the Alzheimer type. A brief review with a case study.
Positron emission tomography in dementia of the Alzheimer type. A brief review with a case study.
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正电子发射断层扫描在阿尔茨海默型痴呆中的应用。
DOI：
10.1001/archinte.1986.00360220219035
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发表时间：
1986
影响因子：
--
通讯作者：
L. Avioli
中科院分区：
文献类型：
--
作者：
G. Berg;C. Grady;M. Sundaram;J. Haxby;A. Moore;J. White;L. Heston;S. Rapoport;L. Avioli
正电子发射断层扫描（PET）已成为研究大脑生理和代谢的一项重要技术。阿尔茨海默型痴呆（DAT）患者已被研究了许多脑成像程序，包括PET。尽管对痴呆患者的PET研究可能具有挑战性，并且难以解释，但研究实验室已经收集了数百名患者的有用数据。本报告的目的是总结这些小组的主要发现，并讨论在马里兰州贝塞斯达国家衰老研究所（NIA）神经科学实验室（LNS）所做的一系列关于家族性数据的PET研究。PET的理论原理和应用综述已发表1,2；基本原理可以简单概括一下。而放射学计算机断层扫描（CT）依赖于通过的x射线束的微分衰减产生的信息的计算机重建
Positron emission tomography (PET) has emerged as an important technique for the in vivo investigation of cerebral physiology and metabolism. Patients with dementia of the Alzheimer type (DAT) have been studied with many brain imaging procedures, including PET. Although PET studies of demented subjects may be challenging to perform and difficult to interpret, research laboratories have collected useful data on a combined patient population of several hundred subjects. The purpose of this presentation is to summarize the major findings of these groups and to discuss serial PET studies done in the Laboratory of Neurosciences (LNS) of the National Institute on Aging (NIA) Bethesda, Md, on a subject with familial DAT. Reviews of the theoretical principles and applications of PET have been published 1,2 ; the basics can be briefly summarized. Whereas radiologic computed tomography (CT) depends on computer reconstruction of information derived from differential attenuation of an x-ray beam passing through
影响因子：
56.9
作者：
PHELPS, ME;MAZZIOTTA, JC
通讯作者：
MAZZIOTTA, JC
使用糖醛合成 2-[F-18]氟-2-脱氧-D-葡萄糖：重新检查。
DOI：
--
发表时间：
1984
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Bida,GT;Satyamurthy,N;Barrio,JR
通讯作者：
Barrio,JR