Dietary patterns and glucose tolerance abnormalities in Japanese men
Dietary patterns and glucose tolerance abnormalities in Japanese men
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DOI：
10.1093/jn/136.5.1352
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发表时间：
2006-05-01
影响因子：
4.2
通讯作者：
Kono, S
中科院分区：
文献类型：
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作者：
Mizoue, T;Yamaji, T;Kono, S
西方的饮食模式似乎增加了患糖尿病的风险，但饮食模式在亚洲人群中的作用尚不清楚。我们调查了日本男性的主要饮食模式和糖耐量状态之间的关系。异常包括空腹血糖受损、糖耐量受损和2型糖尿病。受试者是2106名日本男性，他们在退休前的健康检查中接受了75克口服葡萄糖耐量测试。在测试前，使用74个项目的FFQ获得关于饮食的信息。通过因子分析得出了三种饮食模式：1)高乳制品、高水果和蔬菜、高淀粉、低酒精模式；2)动物性食物模式；3)日本模式。我们使用Logistic回归分析估计优势比(OR)，并对潜在的混杂变量进行调整。与最低的四分位数相比，高乳制品、高水果和蔬菜、高淀粉、低酒精的模式与第二、三、四分位数的糖耐量异常(空腹血糖受损、糖耐量受损或2型糖尿病)的OR值分别为0.80(95%CI=0.62-1.04)、0.71(95%CI=0.54-0.92)和0.51(95%CI=0.38-0.67)呈显著负相关(P<0.0001)。对于每一种糖耐量异常以及糖尿病危险因素分层的亚组，这种反向关联是一致的。日本人的饮食模式与糖耐量受损呈正相关(趋势P=0.048)。经常食用奶制品、水果和蔬菜，但酒精摄入量低的饮食模式可能与糖耐量异常的风险降低有关。
The Western dietary pattern appears to confer diabetes risk, but the role of dietary patterns in Asian populations remains unclear. We investigated the association between major dietary patterns and the glucose tolerance status of Japanese men. Abnormalities included impaired fasting glucose, impaired glucose tolerance, and type 2 diabetes. Subjects were 2106 Japanese men who were administered a 75-g oral glucose tolerance test at their preretirement health check-ups. Information about diet was obtained using a 74-item FFQ before the test. Three dietary patterns were generated by factor analysis: 1) a high-dairy, high-fruit and -vegetable, high-starch, low-alcohol pattern; 2) an animal food pattern; and 3) a Japanese pattern. We used logistic regression analysis to estimate odds ratios (OR) with adjustment for potential confounding variables. A significant inverse association was found for the high-dairy, high-fruit and -vegetable, high-starch, low-alcohol pattern (P for trend < 0.0001); the OR of having a glucose tolerance abnormality (impaired fasting glucose, impaired glucose tolerance, or type 2 diabetes) for the 2nd, 3rd, and 4th quartiles were 0.80 (95% Cl = 0.62-1.04), 0.71 (95% Cl = 0.54-0.92), and 0.51 (95% Cl = 0.38-0.67), respectively, compared with the lowest quartile. The inverse association was consistent for each glucose tolerance abnormality as well as across subgroups stratified by risk factors for diabetes. The Japanese dietary pattern was positively associated with impaired glucose tolerance (P for trend = 0.048). A dietary pattern characterized by frequent consumption of dairy products and fruits and vegetables but low alcohol intake may be associated with a decreased risk of developing a glucose tolerance abnormality.