Millimeter-scale genetic gradients and community-level molecular convergence in a hypersaline microbial mat.
Millimeter-scale genetic gradients and community-level molecular convergence in a hypersaline microbial mat.
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DOI：
10.1038/msb.2008.35
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发表时间：
2008
影响因子：
9.9
通讯作者：
Hugenholtz, Philip
中科院分区：
文献类型：
--
作者：
Kunin, Victor;Raes, Jeroen;Harris, J Kirk;Spear, John R;Walker, Jeffrey J;Ivanova, Natalia;von Mering, Christian;Bebout, Brad M;Pace, Norman R;Bork, Peer;Hugenholtz, Philip
为了研究结构化微生物群落的遗传分层程度，我们比较了墨西哥格雷罗内格罗的遗传复杂的高盐垫的10个连续层的宏基因组。我们发现了明显的毫米级遗传梯度，这与垫的物理化学特征相一致。尽管有这些梯度，所有层显示出几乎相同的酸移等电点的配置文件，由于氨基酸使用的分子收敛，表明高盐度强制执行压倒一切的选择性压力垫社区。
To investigate the extent of genetic stratification in structured microbial communities, we compared the metagenomes of 10 successive layers of a phylogenetically complex hypersaline mat from Guerrero Negro, Mexico. We found pronounced millimeter-scale genetic gradients that were consistent with the physicochemical profile of the mat. Despite these gradients, all layers displayed near-identical and acid-shifted isoelectric point profiles due to a molecular convergence of amino-acid usage, indicating that hypersalinity enforces an overriding selective pressure on the mat community.