Developing a cancer-specific geriatric assessment - A feasibility study
Developing a cancer-specific geriatric assessment - A feasibility study
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DOI：
10.1002/cncr.21422
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发表时间：
2005-11-01
期刊：
影响因子：
6.2
通讯作者：
Kornblith, AB
中科院分区：
文献类型：
--
作者：
Hurria, A;Gupta, S;Kornblith, AB
背景。随着美国人口老龄化，越来越需要描述老年癌症患者的“功能年龄”，以便根据实际年龄以外的因素制定治疗决策和对结果进行分层。当前研究的目标是制定一种简短但全面的、主要是自我管理的癌症特异性老年评估措施，并通过以下指标来确定其可行性：1) 能够自行完成测量的患者百分比，2) 完成的时间长度，以及 3) 患者对测量的满意度。 方法。回顾了老年病学和肿瘤学文献，选择了以下领域的有效老年病评估指标：功能状态、合并症、认知、心理状态、社会功能和支持以及营养状况。适用于老年评估测量的标准包括可靠性、有效性、简洁性和自我管理能力。该措施适用于英语流利并在纪念斯隆-凯特琳癌症中心（纽约州纽约）或芝加哥大学（伊利诺伊州芝加哥市）接受化疗的乳腺癌、肺癌、结直肠癌或淋巴瘤患者。结果。该仪器由 43 名患者完成（平均年龄 74 岁；范围 65-87 岁）。大多数人患有 AJCC IV 期疾病 (68%)。完成评估的平均时间为 27 分钟（范围为 8-45 分钟）。大多数患者能够在没有帮助的情况下完成评估的自我管理部分（78%），并对问卷长度感到满意（90%）。年龄 (P = 0.56) 或教育水平 (P = 0.99) 与在没有帮助的情况下完成评估的能力之间没有任何关联。结论。在这个队列中，大多数患者可以在没有帮助的情况下完成这种简短但全面的老年评估。对其普遍性、可靠性和有效性进行前瞻性试验是合理的。
BACKGROUND. As the U.S. population ages, there is an emerging need to characterize the "functional age" of older patients with cancer to tailor treatment decisions and stratify outcomes based on factors other than chronologic age. The goals of the current study were to develop a brief, but comprehensive, primarily self-administered cancer-specific geriatric assessment measure and to determine its feasibility as measured by 1) the percentage of patients able to complete the measure on their own, 2) the length of time to complete, and 3) patient satisfaction with the measure.METHODS. The geriatric and oncology literature was reviewed to choose validated measures of geriatric assessment across the following domains: functional status, comorbidity, cognition, psychological status, social functioning and support, and nutritional status. Criteria applied to geriatric assessment measurements included reliability, validity, brevity, and ability to self-administer. The measure was administered to patients with breast carcinoma, lung carcinoma, colorectal carcinoma, or lymphoma who were fluent in English and receiving chemotherapy at Memorial Sloan-Kettering Cancer Center (New York, NY) or the University of Chicago (Chicago, IL).RESULTS. The instrument was completed by 43 patients (mean age, 74 yrs; range, 65-87 yrs). The majority had AJCC Stage IV disease (68%). The mean time to completion of the assessment was 27 minutes (range, 8-45 mins). Most patients were able to complete the self-administered portion of the assessment without assistance (78%) and were satisfied with the questionnaire length (90%). There was no association noted between age (P = 0.56) or educational level (P = 0.99) and the ability to complete the assessment without assistance.CONCLUSIONS. In this cohort, this brief but comprehensive geriatric assessment could be completed by the majority of patients without assistance. Prospective trials of its generalizability, reliability, and validity are justified.