Double stereodifferentiating aldol reactions of (E) and (Z) lithium enolates, model reactions for polypropionate assemblage

Double stereodifferentiating aldol reactions of (E) and (Z) lithium enolates, model reactions for polypropionate assemblage
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DOI:
10.1016/0040-4039(96)00178-5
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发表时间:
1996-03-18
影响因子:
1.8
通讯作者:
Duffy, JL
Duffy, JL
中科院分区:
化学4区
文献类型:
--
作者:
Evans, DA;Yang, MG;Duffy, JL

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描述了 (E) 和 (Z) 烯醇锂的双立体分化羟醛反应的系统研究。突出显示了那些通过其他基于烯醇化物的羟醛反应无法获得的羟醛加合物的反应物对。
A systematic investigation of the double stereodifferentiating aldol reactions of (E) and (Z) lithium enolates is described. Those reactant pairs that afford aldol adducts inaccessible through other enolate-based aldol reactions are highlighted.