On the meaning and existence of an effective population size

On the meaning and existence of an effective population size
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DOI:
10.1534/genetics.104.026799
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发表时间:
2005-02-01
期刊:
影响因子:
3.3
通讯作者:
Nordborg, M
Nordborg, M
中科院分区:
生物学2区
文献类型:
--
作者:
Sjödin, P;Kaj, I;Nordborg, M

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我们研究了具有随机人口统计或人口结构的模型收敛到时间尺度线性变化的联合模型的条件。我们认为,这是存在有意义的有效人口规模的必要条件。我们发现,当人口波动和合并事件发生在不同的时间尺度上时,这种线性时间尺度变化被获得。人口结构和随机波动的人口规模的简单模型被用来举例说明这些想法,并为条件的含义提供了直观的感觉。
We investigate conditions under which a model with stochastic demography or population structure converges to the coalescent with a linear change in timescale. We argue that this is a necessary condition for the existence of a meaningful effective population size. We find that such a linear timescale change is obtained when demographic fluctuations and coalescence events occur on different timescales. Simple models of population structure and randomly fluctuating population size are used to exemplify the ideas and provide an intuitive feel for the meaning of the conditions.