Expanding the role of surgery in intractable extratemporal pediatric epilepsy

Expanding the role of surgery in intractable extratemporal pediatric epilepsy
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DOI:
10.3171/foc/2008/25/9/e15
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发表时间:
2008-09-01
影响因子:
4.1
通讯作者:
Robinson, Shenandoah
Robinson, Shenandoah
中科院分区:
医学2区
文献类型:
--
作者:
Goyal, Monisha;Robinson, Shenandoah

文献摘要

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儿童癫痫手术的目的不仅是控制癫痫发作,而且是为了减少未来的不良神经后遗症,提高生活质量。如果术前评估显示不一致或多灶性疾病,颅内手术可能被拒绝作为一个可行的治疗选择。当手术治疗不仅作为治愈性治疗,而且作为姑息性治疗提供时,许多不被认为是最佳手术候选人的儿童可能会受益。作者从2001年至2005年在彩虹婴儿和儿童医院接受颅内癫痫手术的57例儿童的连续系列中,详细介绍了3例儿童从这种积极的方法中获益匪浅的病例。显著改善不仅发生在癫痫发作控制,而且在发展和社会功能。
The aim of epilepsy surgery in children is not only to control seizures but also to curtail future adverse neurological sequelae and improve quality of life. If presurgical evaluation demonstrates discordant or multifocal disease, intracranial surgery may be denied as a viable treatment option. When surgical therapy is offered not just as curative but also as palliative therapy, many children not considered optimal surgical candidates may benefit. From a consecutive series of 57 cases involving children who underwent intracranial epilepsy surgery at Rainbow Babies and Children's Hospital during 2001-2005, the authors present in detail 3 cases involving children who benefited significantly from such an aggressive approach. Marked improvement occurred not only in seizure control, but also in developmental and social functioning.