An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.
An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.
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DOI：
10.1183/16000617.00000315
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发表时间：
2015-06
影响因子：
7.5
通讯作者：
ZuWallack, Richard L
中科院分区：
文献类型：
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作者：
Celli, Bartolome R;Decramer, Marc;Wedzicha, Jadwiga A;Wilson, Kevin C;Agusti, Alvar A;Criner, Gerard J;MacNee, William;Make, Barry J;Rennard, Stephen I;Stockley, Robert A;Vogelmeier, Claus;Anzueto, Antonio;Au, David H;Barnes, Peter J;Burgel, Pierre-Regis;Calverley, Peter M;Casanova, Ciro;Clini, Enrico M;Cooper, Christopher B;Coxson, Harvey O;Dusser, Daniel J;Fabbri, Leonardo M;Fahy, Bonnie;Ferguson, Gary T;Fisher, Andrew;Fletcher, Monica J;Hayot, Maurice;Hurst, John R;Jones, Paul W;Mahler, Donald A;Maltais, Francois;Mannino, David M;Martinez, Fernando J;Miravitlles, Marc;Meek, Paula M;Papi, Alberto;Rabe, Klaus F;Roche, Nicolas;Sciurba, Frank C;Sethi, Sanjay;Siafakas, Nikos;Sin, Don D;Soriano, Joan B;Stoller, James K;Tashkin, Donald P;Troosters, Thierry;Verleden, Geert M;Verschakelen, Johny;Vestbo, Jorgen;Walsh, John W;Washko, George R;Wise, Robert A;Wouters, Emiel F M;ZuWallack, Richard L
慢性阻塞性肺疾病（COPD）是世界范围内发病率、死亡率和资源使用的主要原因。这份美国胸科学会（ATS）/欧洲呼吸学会（ERS）官方研究声明的目的是描述与诊断、评估和管理相关的证据;确定知识差距;并为未来的研究提出建议。其目的不是提供关于COPD诊断和管理的临床实践建议。临床医生、研究人员和具有COPD专业知识的患者倡导者被邀请参加。对Medline进行了文献检索，并选择了认为相关的研究。这次搜索并不是对证据的系统审查。对现有证据进行了评估和总结，然后确定了突出的知识差距。通过讨论和达成共识，制定了针对COPD所有领域证据中重要差距的研究建议。在COPD的诊断、评估和管理以及对其发病机制的理解方面已经取得了很大的进步。尽管如此，许多重要问题仍然没有答案。ATS/ERS研究声明强调了领先的临床医生，研究人员和患者倡导者认为将对以患者为中心的结果产生最大影响的研究类型。ATS/ERS声明强调将对COPD患者结局产生最大影响的研究领域http://ow.ly/LXW2J
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient-centred outcomes. ATS/ERS statement highlighting research areas that will have the greatest impact on patient-centred outcomes in COPD http://ow.ly/LXW2J