Multiple RNA polymerase holoenzymes exert transcriptional specificity in Bacillus subtilis.
Multiple RNA polymerase holoenzymes exert transcriptional specificity in Bacillus subtilis.
复制标题
多种 RNA 聚合酶全酶在枯草芽孢杆菌中发挥转录特异性。
DOI：
10.1016/0003-9861(82)90084-4
复制
发表时间：
1982
影响因子：
3.9
通讯作者：
Doi,RH
中科院分区：
文献类型：
--
作者：
Doi,RH
革兰氏阳性孢子细菌枯草芽孢杆菌具有复杂的转录装置，在其营养生长过程中由至少三种不同的全酶组成，在孢子形成过程中由至少一种新的全酶组成。多种形式的全酶含有分子量范围为28,000至55,000的西格玛因子。碱基序列分析表明，这些全酶识别的启动子在-35和-10区域有所不同。因此，该生物体中基因表达的调节至少部分取决于全酶家族和启动子谱组之间的转录特异性。
The Gram-positive sporulating bacterium,Bacillus subtilis, has a complex transcriptional apparatus consisting of at least three different holoenzymes during its vegetative growth and at least one new holoenzyme during sporulation. The multiple forms of holoenzyme contain sigma factors whose molecular weights range from 28,000 to 55,000. Base sequence analyses have revealed that the promoters recognized by these holoenzymes differ in their −35 and −10 regions. Thus regulation of gene expression in this organism depends at least in part on transcriptional specificity between a family of holoenzymes and sets of promoter spectra.