Non-communicable diseases at a regional hospital in Nepal: Findings of a high burden of alcohol-related disease
Non-communicable diseases at a regional hospital in Nepal: Findings of a high burden of alcohol-related disease
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DOI：
10.1016/j.alcohol.2016.10.008
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发表时间：
2016-12-01
期刊：
影响因子：
2.3
通讯作者：
Risnes, K.
中科院分区：
文献类型：
--
作者：
Amundsen, M. S.;Kirkeby, T. M. G.;Risnes, K.
最近的全球疾病负担报告发现，全球死亡和残疾的很大一部分可归因于饮酒。因此，可能令人惊讶的是，很少有研究报告了“低收入环境”中酒精相关疾病的负担。最近对尼泊尔非传染性疾病负担的证据进行了审查，得出的结论是，仍然缺乏数据，特别是描述酒精相关疾病负担的数据。因此，我们在此报告了尼泊尔一家地区医院住院患者的非传染性疾病负担，特别是ARDs。我们进行了一项回顾性的图表回顾，包括四个月期间所有出院患者的详细信息。建立了一个包含社会人口统计信息和出院诊断的本地数据库。所有医生指定的出院诊断回顾性分配ICD-10代码。该研究共纳入1139名住院成人患者，其中三分之一为非传染性疾病（n = 332）。主要的非传染性疾病为慢性阻塞性肺疾病（COPD） （n = 148, 45%）和ARDs （n = 57, 17%）。患有ARD的患者通常表现为肝硬化的迹象，并且通常是来自特定种族的年轻男性，中位年龄为43岁。这些数据表明，在尼泊尔的一家地区医院中，相对年轻的男性中与酒精有关的严重器官衰竭是导致非传染性疾病高比例的原因。这些发现新颖而令人震惊，值得进一步研究，以确定尼泊尔和其他类似低收入国家ARDs和酒精使用的负担。(C) 2016年作者。Elsevier Inc.出版。
Recent global burden of disease reports find that a major proportion of global deaths and disability worldwide can be attributed to alcohol use. Thus, it may be surprising that very few studies have reported on the burden of alcohol-related disease in "low income settings. The evidence of non communicable disease (NCD) burden in Nepal was recently reviewed and concluded that data is still lacking, particularly to describe the burden of alcohol-related diseases (ARDs). Therefore, here we report on NCD burden and specifically ARDs, in hospitalized patients at a regional hospital in Nepal. We conducted a retrospective chart-review that included detailed information on all discharged patients during a four month period. A local database that included sociodemographic information and diagnoses at discharge was established. All doctor-assigned discharge diagnoses were retrospectively assigned ICD-10 codes. A total of 1,139 hospitalized adult patients were included in the study and one third of these were NCDs (n = 332). The main NCDs were chronic obstructive pulmonary disease (COPD) (n = 148, 45%) and ARDs (n = 57, 17%). Patients with ARD often presented with signs of liver cirrhosis and were typically younger men, with a median age at 43 years, from specific ethnic groups. These data demonstrate that severe alcohol-related organ failure in relatively young men contributed to a high proportion of NCDs in a regional hospital in Nepal. These findings are novel and alarming and warrant further studies that can establish the burden of ARDs and alcohol use in Nepal and other similar low-income countries. (C) 2016 The Authors. Published by Elsevier Inc.