Male patients with adult spinal deformity: sex differences in demographics, radiography, and complications

Male patients with adult spinal deformity: sex differences in demographics, radiography, and complications
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DOI:
10.1007/s43390-024-01023-6
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发表时间:
2024-12-17
期刊:
影响因子:
1.800
通讯作者:
Yukihiro Matsuyama
Yukihiro Matsuyama
中科院分区:
医学4区
文献类型:
--
作者:
Xuepeng Wei;Go Yoshida;Tomohiko Hasegawa;Yu Yamato;Tomohiro Banno;Hideyuki Arima;Shin Oe;Koichiro Ide;Tomohiro Yamada;Kenta Kurosu;Yukihiro Matsuyama

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本研究旨在调查成人脊柱畸形(ASD)手术中人口统计学、影像学和围手术期并发症的性别相关差异,该回顾性队列、单中心研究纳入了接受胸椎至髂骨长器械融合术治疗ASD的患者,随访至少2年。分析术前合并症、围手术期并发症和术后机械并发症的发生率,在323例患者中,ASD在女性中更常见(85.8%)。女性患者的T评分低于男性患者(−1.6 ± 1.1 vs.− 0.8 ± 1.0,<i>p</i>= 0.02)。与女性患者相比,男性患者的退行性脊柱后凸发生率较低(83.4% vs. 65.2%,<i>p</i>= 0.004),但神经肌肉疾病发生率较高(7.6% vs. 21.7%,<i>p</i>= 0.003)。男性患者表现出较高的心血管疾病患病率(4.0% vs. 13.5%,<i>p</i>= 0.034)和血液透析患病率(2.5% vs. 10.8%,<i>p</i>= 0.035)。此外,男性患者的Charlson合并症指数高于女性患者(0.8 ± 1.1 vs. 1.4 ± 1.1,<i>p</i>= 0.001)。此外,男性患者的手术部位感染围手术期并发症更高(5.1% vs. 15.2%,<i>p</i>= 0.018)。然而,近端交界失败(43.3% vs. 39.1%,<i>p</i>= 0.595)和棒断裂(27.8% vs. 26.1%,<i>p</i>= 0.81)的发生率没有差异。ASD男性患者表现出神经肌肉疾病、术前合并症和手术部位感染的频繁病理,需要仔细的术前检查和术中护理。
This study aimed to investigate sex-related differences in demographics, radiography, and perioperative complications in adult spinal deformity (ASD) surgeries.This retrospective cohort, single-center study enrolled patients who underwent long-instrumented fusion from the thoracic spine to the ilium for ASD, with a minimum follow-up of 2 years. The incidence of preoperative comorbidities, perioperative complications, and postoperative mechanical complications was analyzed.Of the 323 patients, ASD was more common in females (85.8%). The T-score in female patients was lower than that in male patients (−1.6 ± 1.1 vs.− 0.8 ± 1.0, <i>p</i> = 0.02). Male patients demonstrated lower rates of degenerative kyphoscoliosis (83.4% vs. 65.2%, <i>p</i> = 0.004) but higher rates of neuromuscular disease (7.6% vs. 21.7%, <i>p</i> = 0.003) than female patients. Male patients exhibited higher prevalence of cardiovascular disease (4.0% vs. 13.5%, <i>p</i> = 0.034) and hemodialysis (2.5% vs. 10.8%, <i>p</i> = 0.035). Additionally, male patients had a higher Charlson Comorbidity Index than female patients (0.8 ± 1.1 vs. 1.4 ± 1.1, <i>p</i> = 0.001). Moreover, male patients showed higher perioperative complications in surgical site infection (5.1% vs. 15.2%, <i>p</i> = 0.018). However, the incidence of proximal junctional failure (43.3% vs. 39.1%, <i>p</i> = 0.595) and rod fracture (27.8% vs. 26.1%, <i>p</i> = 0.81) was not different.Male patients with ASD demonstrated frequent pathology of neuromuscular disease, preoperative comorbidities, and surgical site infection, necessitating careful preoperative checkups and intraoperative care.