X-ray luminescence optical tomography imaging: experimental studies.
X-ray luminescence optical tomography imaging: experimental studies.
复制标题
DOI：
10.1364/ol.38.002339
复制
发表时间：
2013-07-01
期刊：
影响因子：
3.6
通讯作者：
Cherry SR
中科院分区：
文献类型：
--
作者：
Li C;Di K;Bec J;Cherry SR
我们提出了一种混合成像方式，x射线发光光学层析成像(XLOT)，其中准直的x射线束被用来激发基于磷光体的造影剂。使用已知的X射线束位置和空间范围作为先验，从光学信号重建图像。我们利用深部目标的体模实验进行了XLOT实验，结果表明，当深度从4.2 mm变化到7.7 mm时，重建的信号变化了12%。对于简单的源分布，我们发现只需两个正交投影测量就足以进行XLOT重建。
We present a hybrid imaging modality, x-ray luminescence optical tomography (XLOT), in which collimated x-ray beams are used to excite phosphor-based contrast agents. Images are reconstructed from the optical signals, using the known x-ray beam location and spatial extent as priors. We demonstrate XLOT using phantom experiments with deep targets and show that the reconstructed signal varies by <12% when the depth changes from 4.2 to 7.7 mm. For simple source distributions, we find as few as two orthogonal projection measurements are sufficient for XLOT reconstruction.