Rest-activity rhythms across the lifespan: cross-sectional findings from the US representative National Health and Nutrition Examination Survey.
Rest-activity rhythms across the lifespan: cross-sectional findings from the US representative National Health and Nutrition Examination Survey.
复制标题
整个生命周期的休息活动节律：美国代表性国家健康和营养检查调查的横断面调查结果。
DOI：
10.1093/sleep/zsad220
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发表时间：
2023
期刊：
影响因子：
5.6
通讯作者：
Kossowsky,Joe
中科院分区：
文献类型：
--
作者：
Wallace,DanielleA;Johnson,DaynaA;Redline,Susan;Sofer,Tamar;Kossowsky,Joe
研究目的静息-活动节律（RAR）可能标志着发育、衰老和身心健康。了解它们在人与人之间的差异可能会为干预和健康促进工作提供信息。然而，整个生命周期的RAR特征尚未得到充分研究。因此，我们调查了RAR测量与人口统计学和生活方式因素之间的关联，在美国的全国代表性study.MethodsRAR指标的日间稳定性（IS），日内变异性（IV），相对振幅（RA），以及高（M10）和低（L5）的平均幅度和定时活动来自2011年至2012年和2013年至2014年国家健康和营养检查调查（NHANES）的活动记录数据。人口加权线性和逻辑回归模型进行了拟合，以检查年龄，性别，吸烟，饮酒，季节，体重指数（BMI），收入与贫困比，种族/民族与RAR的关联。结果在n = 12 526名NHANES参与者（3-≥80岁）中，IS（较高=更大的日常规律性）和RA（较高=更大的节律强度）通常随年龄而降低，男性较低，而IV（较高=更大的节律碎片）随年龄而增加（p<0. 05）。在儿童和青少年时期观察到RAR轨迹的动态变化。收入、BMI、吸烟和饮酒与RAR指标以及儿童和青少年的季节相关（p< 0.05）。RAR也不同的种族/民族（p< 0.05），最初的轨迹分歧在童年和持续到adult.ConclusionsRAR不同的人口和健康相关因素，代表可能的窗口，公共卫生干预和睡眠健康促进。种族/民族的RAR差异开始于儿童期，在青春期早期明显，并持续整个成年期。
Study ObjectivesRest-activity rhythms (RAR) may mark development, aging, and physical and mental health. Understanding how they differ between people may inform intervention and health promotion efforts. However, RAR characteristics across the lifespan have not been well-studied. Therefore, we investigated the association between RAR measures with demographic and lifestyle factors in a US nationally representative study.MethodsRAR metrics of interdaily stability (IS), intradaily variability (IV), relative amplitude (RA), and mean amplitude and timing of high (M10) and low (L5) activity were derived from 2011 to 2012 and 2013 to 2014 National Health and Nutrition Examination Survey (NHANES) actigraphy data. Population-weighted linear and logistic regression models were fit to examine the associations of age, gender, smoking, alcohol, season, body mass index (BMI), income-to-poverty ratio, and race/ethnicity with RAR. Significance was based on a false-discovery rate-correctedP-value of <0.05.ResultsAmongn= 12 526 NHANES participants (3–≥80 years), IS (higher = greater day-to-day regularity) and RA (higher = greater rhythm strength) generally decreased with age and were lower among males, whereas IV (higher = greater rhythm fragmentation) increased with age (p< 0.05). Dynamic changes in RAR trajectories were observed during childhood and adolescence. Income, BMI, smoking, and alcohol use were associated with RAR metrics, as well as season among children and teenagers (p< 0.05). RAR also differed by race/ethnicity (p< 0.05), with trajectories initially diverging in childhood and continuing into adulthood.ConclusionsRAR differed by demographic and health-related factors, representing possible windows for public health intervention and sleep health promotion. RAR differences by race/ethnicity begin in childhood, are evident in early adolescence, and persist throughout adulthood.