Multinanoparticle Translocations in Phospholipid Membranes: Translocation Modes and Dynamic Processes
Multinanoparticle Translocations in Phospholipid Membranes: Translocation Modes and Dynamic Processes
复制标题
磷脂膜中的多纳米颗粒易位：易位模式和动态过程
DOI：
10.1063/1674-0068/cjcp1910174
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发表时间：
2020
影响因子：
1
通讯作者：
Shi-ben Li
中科院分区：
文献类型：
--
作者：
Ping-ping Xia;Yue Shan;Lin-li He;Yong-yun Ji;Xiang-hong Wang;Shi-ben Li
通过耗散粒子动力学模拟研究了多纳米颗粒与溶液中磷脂膜的相互作用。所选纳米颗粒具有球形或圆柱形，它们在动力学过程中具有不同的初始速度。根据其在动力学过程中的特点定义了几种易位模式，其中基于颗粒与磷脂膜之间的相互作用强度构建了相图。 此外，在各种易位模式的动力学过程中研究了系统能量和回转半径等几个参数。结果阐明了生物过程中多粒子与膜相互作用的影响。
Multinanoparticles interacting with the phospholipid membranes in solution were studied by dissipative particle dynamics simulation.The selected nanoparticles have spherical or cylindrical shapes, and they have various initial velocities in the dynamical processes.Several translocation modes are defined according to their characteristics in the dynamical processes, in which the phase diagrams are constructed based on the interaction strengths between the particles and membranes and the initial velocities of particles.Furthermore, several parameters, such as the system energy and radius of gyration, are investigated in the dynamical processes for the various translocation modes.Results elucidate the effects of multiparticles interacting with the membranes in the biological processes.