Neovascular glaucoma: a retrospective review from a tertiary center in China.
Neovascular glaucoma: a retrospective review from a tertiary center in China.
复制标题
新生血管性青光眼：中国三级中心的回顾性研究
DOI：
10.1186/s12886-016-0190-8
复制
发表时间：
2016-01-27
影响因子：
2
通讯作者：
Wang Q
中科院分区：
文献类型：
--
作者：
Liao N;Li C;Jiang H;Fang A;Zhou S;Wang Q
本研究的目的是报道中国某三级眼科保健中心新生血管性青光眼(NVG)的患病率、病因、治疗和转归。方法回顾2003年至2014年温州医科大学就诊的NVG患者的病历。成功定义为眼压在6~21 mm Hg之间，没有局部或全身性青光眼药物治疗，并保留现有视力(VA)。结果8306例青光眼患者中有483例(5.8%)诊断出NVG。报告了284名患者的310只眼的病因。干预依赖于保险和个人财务；报告了138名患者的149只眼的结果，这些患者的完整数据符合随访要求。糖尿病视网膜病变(DR，39.7%)是NVG的主要原因。Kaplan Meier生存分析显示，1年成功率为84.8%，3年成功率为47.5%，5年成功率为21.9%。青光眼引流装置(GDD)103眼，经巩膜睫状体光凝(TSCPC)22眼。结论NVG占中国三级医院青光眼患者的5.8%。糖尿病视网膜病变被确定为最常见的原因，这可能反映了中国糖尿病患病率的上升。手术干预在一定程度上取决于保险状况和个人财务状况。GDD是最常见的外科干预措施，也是最常见的并发症。
BackgroundThe purpose of this study is to report the prevalence, etiology, treatment and outcomes of neovascular glaucoma (NVG) in a tertiary care ophthalmic center in China.MethodsMedical records of patients diagnosed as NVG at the Wenzhou Medical University between 2003 and 2014 were reviewed. Success was defined as IOP between 6 and 21 mmHg without topical or systemic glaucoma medications with retention of presenting visual acuity (VA).ResultsNVG was diagnosed in 483 of 8306 (5.8 %) of all glaucoma patients. Etiology is reported for all 310 eyes of 284 patients managed in the department. Interventions depended on insurance as well as personal finances; outcomes are reported for the 149 eyes of 138 patients with complete data that met follow up requirements. Diabetic retinopathy (DR,39.7 %) was the major cause of NVG. Kaplan Meier survival analysis showed a success rate of 84.8 % at 1 year, 47.5 % at 3 years and 21.9 % at 5 years. Major interventions included glaucoma drainage device (GDD) in 103 eyes and trans-scleral cyclophotocoagulation (TSCPC) in 22 eyes. Complications were more common in the GDD group.ConclusionsNVG comprised 5.8 % of glaucoma patients seen in a tertiary Chinese hospital. DR was identified as the commonest cause and probably reflects the increasing prevalence of diabetes in China. Surgical interventions were partly determined by insurance status and personal finances. GDD was the commonest surgical intervention used and also had the most complications.