Characterization of non‐linear relationship between total and unbound serum concentrations of valproic acid in epileptic children
Characterization of non‐linear relationship between total and unbound serum concentrations of valproic acid in epileptic children
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DOI：
10.1111/j.1365-2710.2008.00885.x
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发表时间：
2008-02
影响因子：
2
通讯作者：
Satoshi Ueshima;Tetsuya Aiba;Takashi Makita;Shigeki Nishihara;Y. Kitamura;Yuji Kurosaki;Hiromu Kawasaki;T. Sendo;Yoko Ohtsuka;Yutaka Gomita
中科院分区：
文献类型：
--
作者：
Satoshi Ueshima;Tetsuya Aiba;Takashi Makita;Shigeki Nishihara;Y. Kitamura;Yuji Kurosaki;Hiromu Kawasaki;T. Sendo;Yoko Ohtsuka;Yutaka Gomita
目的：建立回归方程，根据总血清浓度正确估计丙戊酸（VPA）的未结合血清浓度;回顾性描述总血清浓度和未结合血清浓度之间的关系。
Objective: To establish a regression equation to properly estimate the unbound serum concentration of valproic acid (VPA) from its total serum concentration; the relationship between total and unbound serum VPA concentrations was retrospectively characterized.