Replication

Replication
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DOI:
10.1016/b978-0-12-801946-7.00004-3
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发表时间:
2015-07-24
期刊:
Principles of Molecular Virology
影响因子:
--
通讯作者:
Cann AJ
Cann AJ
中科院分区:
其他
文献类型:
--
作者:
Cann AJ

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This chapter provides an overview of the key stages in virus replication, including the historic experiments which resulted in our present understanding. It describes, step by step, how replication unfolds, starting with the initial interaction between the virus and a host cell and finishing with the release of infectious virus particles which can go on and infect new cells. Since these processes are essential in the replication cycle, understanding how they can be blocked specifically without damaging the host cell is the key to understanding how antiviral drugs work. Explain the phases of virus replication. Describe the key experiments which allowed us to understand what happens during replication. Discuss how drugs which block these processes can be used to combat virus infections.