trans-spliceosomal U6 RNAs of Crithidia fasciculata and Leptomonas seymouri: deviation from the conserved ACAGAG sequence and potential base pairing with spliced leader RNA
trans-spliceosomal U6 RNAs of Crithidia fasciculata and Leptomonas seymouri: deviation from the conserved ACAGAG sequence and potential base pairing with spliced leader RNA
复制标题
Crithidia fasciculata 和 Leptomonas seymouri 的反式剪接体 U6 RNA:与保守 ACAGAG 序列的偏差以及与剪接前导 RNA 的潜在碱基配对
DOI:
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发表时间:
1994
影响因子:
5.3
通讯作者:
Albrecht Bindereif
中科院分区:
文献类型:
--
作者:
Guoliang Xu;Björn Wieland;Albrecht Bindereif
U6 RNA genes from the trypanosomatids Crithidia fasciculata and Leptomonas seymouri have been isolated and sequenced. As in Trypanosoma brucei, the U6 RNA genes in both C. fasciculata and L. seymouri are arranged in close linkage with upstream tRNA genes. The U6 RNA sequences from C. fasciculata and L. seymouri deviate in five and three positions, respectively, from the published T. brucei sequence. Interestingly, both C. fasciculata U6 RNA genes carry a C-->T change at the second position of the ACAGAG hexanucleotide sequence, which is important for splicing function and has been considered phylogenetically invariable. A compensatory base change of the C. fasciculata spliced leader RNA at the highly conserved 5' splice site position +5, G-->A, suggests that an interaction between the 5' splice site region and U6 RNA recently proposed for the yeast cis-splicing system may also occur in trans splicing.
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DOI:
--
发表时间:
1993
期刊:
The Journal of parasitology
影响因子:
--
作者:
Bellofatto,V;Hartree,DE;Torres-Munoz,J
通讯作者:
Torres-Munoz,J
影响因子:
14.9
作者:
Aksoy,S
通讯作者:
Aksoy,S
影响因子:
14.9
作者:
Muhich,ML;Hughes,DE;Simpson,AM;Simpson,L
通讯作者:
Simpson,L
影响因子:
14.9
作者:
Bellofatto,V;Cooper,R;Cross,GA
通讯作者:
Cross,GA
影响因子:
10.5
作者:
Watkins,KP;Agabian,N
通讯作者:
Agabian,N