Autologous blood for pleurodesis in recurrent and chronic spontaneous pneumothorax.
Autologous blood for pleurodesis in recurrent and chronic spontaneous pneumothorax.
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自体血用于复发性和慢性自发性气胸的胸膜固定术。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
Robinson Cl
中科院分区：
文献类型：
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作者：
Robinson Cl
对于复发性气胸，开放手术可能需要切除或缝合大疱。同时，为了刺激粘连，可以用纱布、用于引起炎症的化学品或进行部分胸膜切除术来磨损胸膜。如果肺出现厚皮，出现大出血（血气胸）或出现大疱，则需要手术剥除肺皮质。有时，慢性气胸是由于粘连撑开大疱而引起的持续性渗漏。粘连可以在胸腔镜检查时用透热法切开，渗漏将关闭。许多化学试剂已被用于促进粘连：碘化甘油粉、银银、50%葡萄糖和水、Atabrine、氮芥和四环素。在该系列中，在肺完全扩张后，通常在使用心尖胸管后，使用1 - 3次每次50 ml自体血滴注。在25例困难、慢性或复发性气胸患者中，21例（85%）手术成功。这是一种实用而简单的方法，导致化学胸膜固定术，没有严重的副作用。
Open operation for recurrent pneumothorax may be necessary to resect or oversew a bulla. At the same time, to stimulate adhesions, the pleura may be abraded with gauze, chemicals used to cause inflammation or a partial pleurectomy performed. Operation is necessary to decorticate the lung if it has developed a thick peel, in the presence of gross bleeding (hemopneumothorax) or if a large bulla is present. Occasionally, a chronic pneumothorax is due to a persistent leak caused by an adhesion holding open a bulla. The adhesion may be cut at thoracoscopy, using diathermy, and the leak will close. Many chemical agents have been used to encourage adhesions: iodized talcum powder, silver nitrate, 50% glucose and water, Atabrine, nitrogen mustard and tetracycline. In this series, one to three instillations each of 50 ml of autologous blood were used after the lung was fully expanded, usually after the use of an apical chest tube. This procedure was successful in 21 (85%) of 25 patients with difficult, chronic or recurrent pneumothoraces. It is a practical and easy method of causing a chemical pleurodesis, without serious side effects.