Detrended fluctuation analysis of laser Doppler flowmetry time series
Detrended fluctuation analysis of laser Doppler flowmetry time series
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DOI：
10.1016/j.mvr.2009.07.005
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发表时间：
2009-12-01
影响因子：
3.1
通讯作者：
Esen, Hamza
中科院分区：
文献类型：
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作者：
Esen, Ferhan;Aydin, Guelsuen Soenmez;Esen, Hamza
通过计算缩放指数 α，激光多普勒血流 (LDF) 时间序列的去趋势波动分析 (DFA) 似乎可以提高微血管功能障碍的预后能力。在本研究中，通过 DFA 评估篮球运动员与久坐对照组相比，长期剧烈活动引起的微血管功能变化。在休息和局部加热期间测量前臂皮肤血流量。确定了与心脏、心肺和局部因素相对应的三个标度指数，即三个回归线的斜率。局部缩放指数始终约为 1，alpha = 1.01 +/- 0.15。在对照组中，局部加热没有改变。然而，我们在篮球运动员中发现了一条具有两个缩放指数（alpha(1) = 1.06 +/- 0.01 和 alpha(2) = 0.75 +/- 0.01）的折线。通过局部加热，折线变成具有一个缩放指数 (alpha(T) = 0.94 +/- 0.01）的单线。标度指数 alpha(2) 和 alpha(T) 小于 1，表明由于局部机制整合的丧失而导致血流的长程相关性降低，并表明内皮功能障碍是最有可能的候选者。从静息时的基线 LDF 信号评估微血管功能是 DFA 优于使用诱发相对信号幅度变化的其他方法（无论是否是光谱）的方法。 (C) 2009 Elsevier Inc. 保留所有权利。
Detrended fluctuation analysis (DFA) of laser Doppler flow (LDF) time series appears to yield improved prognostic power in microvascular dysfunction, through calculation of the scaling exponent, alpha. In the present study the long lasting strenuous activity-induced change in microvascular function was evaluated by DFA in basketball players compared with sedentary control. Forearm skin blood flow was measured at rest and during local heating. Three scaling exponents, the slopes of the three regression lines, were identified corresponding to cardiac, cardio-respiratory and local factors. Local scaling exponent was always approximately one, alpha = 1.01 +/- 0.15. in the control group and did not change with local heating. However, we found a broken line with two scaling exponents (alpha(1) = 1.06 +/- 0.01 and alpha(2) = 0.75 +/- 0.01) in basketball players. The broken line became a single line having one scaling exponent (alpha(T) = 0.94 +/- 0.01) with local heating. The scaling exponents, alpha(2) and alpha(T), smaller than 1 indicate reduced long-range correlation in blood flow due to a loss of integration in local mechanisms and suggest endothelial dysfunction as the most likely candidate. Evaluation of microvascular function from a baseline LDF signal at rest is the superiority of DFA to other methods, spectral or not, that use the amplitude changes of evoked relative signal. (C) 2009 Elsevier Inc. All rights reserved.