MULTIDIMENSIONAL-ANALYSIS OF GEOGRAPHIC GENETIC-STRUCTURE
MULTIDIMENSIONAL-ANALYSIS OF GEOGRAPHIC GENETIC-STRUCTURE
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DOI：
10.2307/2992184
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发表时间：
1990-09-01
期刊：
影响因子：
--
通讯作者：
LESSA, EP
中科院分区：
文献类型：
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作者：
LESSA, EP
多位点数据是研究群体内和群体间遗传变异的重要信息来源。层次分析法被广泛应用于多位点数据的检验。然而，分层（表型或系统发育）算法来描绘地理遗传结构，特别是物种内的局限性，早已被认识到。遗传距离的多维标度在这里被检查作为地理遗传结构的探索性分析的有用技术。多维缩放的优点和局限性进行了讨论，并说明了重新分析的两个案例研究：口袋地鼠（Bottae）的中部加州“遗传组”和杂交区的两个染色体形式的帐篷制作蝙蝠（Uroderma bilobatum）。多维缩放恢复分层模式时，存在的，是特别有用的发现非层次模式的变化。即使在杂交类群之间没有固定的遗传差异的情况下，也可以通过多维尺度来检查网状和临床变异模式，这一发现为研究地理遗传分歧和物种形成开辟了新的可能性。
Multilocus data are an important source of information on genetic variation within and among populations. Hierarchial techniques are used widely for examining multilocus data. However, the limitations of hierarchial (phenetic or phylogenetic) algorithms to depict geographic genetic structure, particularly within species, have long been recognized. Multidimensional scaling of genetic distances is herein examined as a useful technique for exploratory analysis of geographic genetic structure. The advantages and limitations of multidimensional scaling are discussed and illustrated with reanalysis of two case studies: pocket gophers (Thomomys bottae) of the central California "genetic group" and a hybrid zone of two chromosomal forms of the tent-making bat (Uroderma bilobatum). Multidimensional scaling does recover hierarchical patterns when present and is especially useful to uncover nonhierarchial patterns of variation. The finding that reticular and clinical patterns of variation may be examined via multidimensional scaling even in the absence of fixed genetic differences between hybridizing taxa opens new possibilities for study geographic genetic divergence and speciation.