Long-term effectiveness of arthrocentesis with and without hyaluronic acid injection for treatment of temporomandibular joint osteoarthritis
Long-term effectiveness of arthrocentesis with and without hyaluronic acid injection for treatment of temporomandibular joint osteoarthritis
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DOI：
10.2334/josnusd.17-0423
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发表时间：
2019-03-01
影响因子：
1.9
通讯作者：
Bjornland, Tore
中科院分区：
文献类型：
--
作者：
Bergstrand, Sara;Ingstado, Hanne K.;Bjornland, Tore
本研究评价关节内关节腔穿刺术治疗骨性关节炎的远期疗效，并将单纯关节穿刺术/关节灌洗术与关节穿刺术/关节灌洗术及注射透明质酸进行比较。40名患者符合纳入标准，37名患者完成了长期随访(约4年)。将患者随机分为两组：单纯关节穿刺组(A组，n=17)和透明质酸联合治疗组(AS组，n=20)。进行标准的双针关节穿刺术。在基线和治疗大约4年后测量疼痛和关节声音。从基线到最终随访检查，两组患者的视觉模拟评分(VAS)表明，报告的疼痛显著减少。A组平均VAS评分由降至16(P<；0.001)，AS组由63降至25(P<；0.001)。两组平均最大切牙张开度均显著增加，但组间差异无统计学意义(P=0.223)。两组间关节音无明显改善(A组，P=0.495；AS组，P=0.236)。这两种方法在长期内都显著改善了疼痛和下颌功能。
This study evaluated the long-term effectiveness of intra-articular temporoman dibular joint arthrocentesis for patients with osteoarthritis and compared arthrocentesis/lavage alone with arthrocentesis/lavage and injected hyaluronic acid. Forty patients met the inclusion criteria, and 37 completed long-term follow-up (approximately 4 years). The patients were randomly allocated to two groups: arthrocentesis with lavage alone (A-group, n = 17) or combined with hyaluronic acid treatment (AS-group, n = 20). Standard two-needle arthrocentesis was performed. Pain and joint sounds were measured at baseline and approximately 4 years after treatment. Reported pain, as indicated by visual analogue scale (VAS) score, significantly decreased from baseline to the final follow-up examination in both groups. Mean VAS score decreased from 64 to 16 (P < 0.001) in the A-group and from 63 to 25 (P < 0.001) in the AS-group. Average maximum incisor opening increased significantly in both groups but did not significantly differ between groups (P = 0.223). Joint sounds did not significantly improve within groups (A-group, P = 0.495; AS-group, P= 0.236). Both methods resulted in significant long-term improvements in pain and jaw function.