Nine new tropane alkaloids from Datura stramonium L. identified by GC/MS
Nine new tropane alkaloids from Datura stramonium L. identified by GC/MS
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DOI：
10.1016/j.fitote.2010.09.010
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发表时间：
2011-03-01
期刊：
影响因子：
3.4
通讯作者：
Soulaymani, Abdelmajid
中科院分区：
文献类型：
--
作者：
El Bazaoui, Ahmed;Bellimam, My Ahmed;Soulaymani, Abdelmajid
通过 GC/MS 在曼陀罗器官中鉴定出 67 种托烷生物碱。九种新托烷生物碱，3,7-二羟基-6-丙酰氧基托烷、6,7-脱氢-3-替格洛氧基托烷、3-替格洛氧基-6,7-环氧托烷、3,7-二羟基-6-(2'-甲基丁酰氧基)托烷、6,7-脱氢阿阿托品、3-(3'-甲氧基托丙氧基)托烷、初步鉴定出3-三甲酰氧基-6-异丁酰氧基-7-羟基托烷、3-三甲酰氧基-6-异丁酰氧基托烷、3β-三甲酰氧基-6β-异戊酰氧基托烷。首次报道了曼陀罗属生物碱环托品、二氢子莨菪碱、6,7-脱氢天仙胺和4'-羟基石托碱，以及茄科生物碱6,7-脱氢托品。天仙子胺和东莨菪碱是植物器官中的主要托烷生物碱。 (C) 2010 Elsevier B.V. 保留所有权利。
Sixty seven tropane alkaloids were identified in the organs of Datura stramonium L by GC/MS. Nine new tropane alkaloids, 3,7-dihydroxy-6-propionyloxytropane, 6,7-dehydro-3-tigloyloxytropane, 3-tigloyloxy-6,7-epoxytropane, 3,7-dihydroxy-6-(2'-methylbutyryloxy)tropane, 6,7-dehydroapoatropine, 3-(3'-methoxytropoyloxy)tropane, 3-tigloyloxy-6-isobutyryloxy-7-hydroxytropane, 3-tropoyloxy-6-isobutyryloxytropane,3 beta-tropoyloxy-6 beta-isovaleroyloxytropane were tentatively identified. The alkaloids cyclotropine, dihydroaposcopolamine, 6,7-dehydrohyoscyamine and 4'-hydroxylittorine are reported for the first time for the genus Datura and 6,7-dehydrotropine for the family Solanaceae. Hyoscyamine and scopolamine figure as the major tropane alkaloids in the plant organs. (C) 2010 Elsevier B.V. All rights reserved.