Monte Carlo calculations and experimental measurements of dosimetry parameters of a new 103Pd source.
Monte Carlo calculations and experimental measurements of dosimetry parameters of a new 103Pd source.
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新 103Pd 源剂量学参数的蒙特卡罗计算和实验测量。
DOI：
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Jay J. Fan
中科院分区：
文献类型：
--
作者：
Zuofeng Li;J. Palta;Jay J. Fan
使用 125I（碘）或 103Pd（钯）源进行永久性前列腺植入是治疗早期前列腺癌的常用治疗选择。随着新设计来源的开发和销售用于永久性前列腺植入，必须仔细确定其剂量特征，以保持患者治疗的准确性。本报告介绍了对新可用的 103Pd 种子源进行的剂量学参数的实验测量和蒙特卡罗计算的结果。使用二极管检测器在大型扫描水体模中进行测量。源和探测器的定位是通过扫描水体模中计算机控制的定位机构实现的。新 103Pd 源在水中的剂量率常数是通过用已知空气比释动强度的 125I 源校准的二极管检测器进行测量来确定的。使用二极管检测器测量源的径向剂量函数值。然后使用蒙特卡罗光子输运计算，使用源的精确几何模型来计算剂量率常数、径向剂量函数和各向异性函数的剂量学参数。测量的剂量率常数 0.693 cGy/U-hr 与蒙特卡罗计算值 0.677 cGy/U-hr 非常吻合。这些结果与现有 103Pd 源的数据进行了进一步比较。
Permanent prostate implantation using 125I (iodine) or 103Pd (palladium) sources is a popular treatment option in the management of early prostate cancer. As sources of new designs are developed and marketed for application in permanent prostate implantations, their dosimetric characteristics must be carefully determined in order to maintain the accuracy of patient treatment. This report presents the results of experimental measurements and Monte Carlo calculations of the dosimetric parameters performed for a newly available 103Pd seed source. The measurements were performed in a large scanning water phantom using a diode detector. The positioning of the source and detector was achieved by a computer-controlled positioning mechanism in the scanning water phantom. The dose rate constant in water for the new 103Pd source was determined from measurements with the diode detector calibrated with 125I sources of known air-kerma strength. The radial dose function values for the source were measured using the diode detector. Monte Carlo photon transport calculations were then used to calculate the dosimetric parameters of dose rate constant, radial dose function, and anisotropy function using an accurate geometric model of the source. The measured dose rate constant of 0.693 cGy/U-hr compares well with the Monte Carlo calculated value of 0.677 cGy/U-hr. These results are further compared with data on existing 103Pd sources.
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影响因子：
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作者：
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DOI：
10.1016/0360-3016(87)90302-6
发表时间：
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期刊：
International journal of radiation oncology, biology, physics
影响因子：
--
作者：
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