Hepatocellular carcinoma and cirrhosis - Results of surgical treatment in a European series
Hepatocellular carcinoma and cirrhosis - Results of surgical treatment in a European series
复制标题
DOI：
10.1097/00000658-199603000-00011
复制
发表时间：
1996-03-01
影响因子：
9
通讯作者：
Visa, J
中科院分区：
文献类型：
--
作者：
Fuster, J;GarciaValdecasas, JC;Visa, J
目的分析肝细胞癌（HCC）合并肝硬化患者行肝切除术的疗效。西方中心与这些patients.Methods的经验是短于亚洲series. Forty-eight连续肝硬化和肝癌患者进行肝切除术后，类似的诊断和治疗过程进行了研究。根据病理结果计算生存率和累积复发率。结果影响3年生存率的因素有：切除类型、无血管侵犯、肿瘤大小、无卫星结节和结节数量。影响3年复发率的因素是血管浸润和卫星结节的存在。预后良好的患者有一个良好的生存率与可接受的复发率。结论识别的预后因素可能有助于在选择适当的治疗这些患者肝癌和肝硬化。
Objective The authors analyze the outcomes of patients with hepatocellular carcinoma (HCC) and cirrhosis who underwent liver resections.Background Liver resection is the best option for HCC arising from hepatic cirrhosis. The experience of Western centers with these patients is shorter than the Asian series.Methods Forty-eight consecutive patients with cirrhosis and HCC who underwent liver resections were studied after a similar diagnostic and therapeutic process. Survival and cumulative recurrence were calculated according to pathologic findings.Results Factors influencing survival at 3 years were as follows: type of resection, absence of vascular invasion, size of the tumor, absence of satellite nodules, and the number of nodules. Factors influencing the rate of recurrence at 3 years were the presence of vascular invasion and the presence of satellite nodules. Patients with favorable prognostic factors have a good survival rate with an acceptable recurrence rate.Conclusions Identification of prognostic factors may help in the selection of the appropriate treatment for these patients with HCC and cirrhosis.