Effect of Shexiangbaoxin pills on heart function in patients with chronic ischemia heart failure.
Effect of Shexiangbaoxin pills on heart function in patients with chronic ischemia heart failure.
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DOI：
10.3724/sp.j.1008.2013.00037
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发表时间：
2013-01-01
影响因子：
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通讯作者：
Wu, Z. G.
中科院分区：
文献类型：
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作者：
Ding Ru, Ding Ru;Gui YanPing, Gui YanPing;Wu, Z. G.
目的：探讨麝香保心丸对慢性缺血性心力衰竭患者心功能的影响。方法：将96例稳定型慢性缺血性心力衰竭患者随机分为麝香保心丸组（麝香保心丸加基础治疗）和安慰剂组（安慰剂加基础治疗），疗程24周。比较两组治疗前后左心室射血分数(LVEF)、左心室舒张末期容积(LVEDV)、血清脑钠肽(BNP)水平、6分钟步行试验(6MWT)。结果：麝香保心丸组治疗24周后LVEF增加5.6%（[34.23.5]% vs [36.14.0]%，P
Objective: To investigate the effect of Shexiangbaoxin pills on the heart function of patients with chronic ischemia heart failure. Methods: A total of 96 patients with documented stable chronic ischemia heart failure were evenly randomized into Shexiangbaoxin pill group (Shexiangbaoxin pill plus basic treatment) and placebo group (placebo plus basic treatment) for 24 weeks. The left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVEDV), serum brain natriuretic peptide (BNP) level, and 6 minute walk test (6 MWT) were compared before and after treatment in the two groups. Results: In Shexiangbaoxin pill group, the LVEF was increased by 5.6% after 24 weeks of treatment ([34.23.5]% vs [36.14.0]%, P