Polycyclic musk fragrances in human adipose tissue and human milk.
Polycyclic musk fragrances in human adipose tissue and human milk.
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DOI：
10.1016/0045-6535(96)00321-9
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发表时间：
1996-11
期刊：
影响因子：
8.8
通讯作者：
G. Rimkus;M. Wolf
中科院分区：
文献类型：
--
作者：
G. Rimkus;M. Wolf
采用GC/EI/MS法，在SIM模式下，对14份人体脂肪组织样品和5份母乳样品中的多环麝香香料（取代茚满和四氢萘衍生物）进行了测定。HHCB和AHTN的残留水平分别为16至189微克/千克脂肪和8至58微克/千克脂肪。在少数样品中，还检测到较低水平的ADBI、AHDI和ATII。在类似的硝基麝香，皮肤吸附的这些亲脂性化合物从化妆品和洗涤剂进行了讨论，作为一个可能的污染途径。
Polycyclic musk fragrances - substituted indane and tetraline derivatives - which are intensively utilized in cosmetics and detergents were determined in a total of 14 human adipose tissue samples and 5 human milk samples by GC/El/MS in the SIM mode. The residue levels ranged from 16 to 189 μg/kg fat for HHCB and from 8 to 58 μg/kg fat for AHTN, respectively. In a few samples also ADBI, AHDI and ATII were detected at lower levels. In analogy to the nitro musks, the dermal sorption of these lipophilic compounds from cosmetics and detergents is discussed as a possible contamination route.