Continuing outbreak of hepatitis A linked with intravenous drug abuse in Multnomah County.
Continuing outbreak of hepatitis A linked with intravenous drug abuse in Multnomah County.
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摩特诺玛县甲型肝炎的持续爆发与静脉注射毒品滥用有关。
DOI：
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发表时间：
1988
期刊：
影响因子：
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通讯作者：
Danuta Komorwska
中科院分区：
文献类型：
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作者：
C. Schade;Danuta Komorwska
从1983年到1986年，在俄勒冈州的波特兰发生了一次社区范围的甲型肝炎爆发。在疫情高峰期，25至34岁的男性（最高风险群体）中，按年龄和性别划分的年发病率接近每10万人400例。社区发病率几乎是全国相关发病率的10倍。对1985年最后6个月报告的甲型肝炎病例记录的审查表明，在这段时间内接受调查的病例中，约有一半的年轻人报告有静脉注射毒品的使用史-这一比例比该年龄范围内预期的高出约50倍。海洛因过量死亡的流行和随之而来的B型肝炎发病率的增加，导致人们怀疑这是新静脉吸毒者中与药物滥用相关的肝炎流行病。控制这次疫情很困难，因为最危险的人群不信任公共卫生官员。加强对食品服务机构和学校的监测可能防止了一般人群中的共同来源的暴发;然而，非吸毒人群中的散发病例明显增加。
A communitywide outbreak of hepatitis A occurred in Portland, OR, from 1983 through 1986. At the peak of the outbreak, the age- and sex-specific annual incidence rate approached 400 cases per 100,000 population among men ages 25 to 34, the highest risk group. The community incidence rate was nearly 10 times the relevant national incidence rate. A review of the records concerning cases of hepatitis A reported in the last 6 months of 1985 revealed that about half the number of young adults whose cases were investigated during that time reported a history of intravenous (IV) drug use--a proportion about 50 times greater than expected among persons in that age range. A simultaneous epidemic of overdose deaths from heroin and a concomitant increase in hepatitis B incidence rates led to the suspicion that this was a drug-abuse-associated epidemic of hepatitis among new IV drug users. Control of this outbreak was difficult because the population most at risk was distrustful of public health officials. Increased surveillance in food service establishments and schools might have prevented outbreaks from a common source in the general population; however, an increase of sporadic cases in the nondrug-using population clearly occurred.