VERTEBRAL ENDPLATE CHANGES WITH AGING OF HUMAN VERTEBRAE
VERTEBRAL ENDPLATE CHANGES WITH AGING OF HUMAN VERTEBRAE
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DOI：
10.1097/00007632-198203000-00002
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发表时间：
1982-01-01
期刊：
影响因子：
3
通讯作者：
CAILLIET, R
中科院分区：
文献类型：
--
作者：
BERNICK, S;CAILLIET, R
描述了从出生到73岁的人类椎骨软骨终板的生长层和关节层的连续年龄变化。生长软骨的宽度在16-20岁时逐渐变小。在成年期和进入老年阶段(60-73岁)，终板只由经过钙化的关节软骨组成，然后被骨吸收和替代。在靠近软骨或椎间盘的骨骼的滋养管或间隙中，可以观察到小动脉、毛细血管和小静脉的年龄变化。关节软骨的钙化和较老的椎骨中的血管变化会阻碍营养物质从血液到椎间盘本身的运输。可以观察到胶原纤维从较老的椎体终板长出，进入椎间盘的中段。
Sequential age changes are described within the growth and articular layers of the cartilaginous end-plates of vertebrae from humans aged from birth to 73 yrs. There is a gradual reduction in the width of the growth cartilage up to 16-20 yrs of age. During adulthood and progressing into old age (60-73 yrs), the end-plates consist of only articular cartilage which undergoes calcification followed by resorption and replacement by bone. Age changes are observed in the arterioles, capillaries and venules found in the nutrient canals or spaces of the bone adjacent to the cartilage or disc. Calcification of the articular cartilage and vascular changes seen in the older vertebrae would impede the passage of nutrients from the blood to the disc proper. Collagen fibers are observed arising from the older vertebral end-plates to course into the midregion of the disc.