Chemically functionalized carbon nanotubes as substrates for neuronal growth
Chemically functionalized carbon nanotubes as substrates for neuronal growth
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DOI：
10.1021/nl035193d
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发表时间：
2004-03-01
期刊：
影响因子：
10.8
通讯作者：
Parpura, V
中科院分区：
文献类型：
--
作者：
Hu, H;Ni, YC;Parpura, V
我们报告使用化学修饰的碳纳米管作为培养神经元的基板。神经元的形态特征，直接反映了他们的潜在能力，在突触传递的特点。碳纳米管的化学性质通过将赋予已知特性的不同官能团连接到基底上而系统地变化。通过操纵功能化碳纳米管所携带的电荷，我们能够控制神经元过程的生长和分支模式。
We report the use of chemically modified carbon nanotubes as a substrate for cultured neurons. The morphological features of neurons that directly reflect their potential capability in synaptic transmission are characterized. The chemical properties of carbon nanotubes are systematically varied by attaching different functional groups that confer known characteristics to the substrate. By manipulating the charge carried by functionalized carbon nanotubes we are able to control the outgrowth and branching pattern of neuronal processes.