Safety and efficacy of an insulin infusion protocol designed for the non-intensive care setting.
Safety and efficacy of an insulin infusion protocol designed for the non-intensive care setting.
复制标题
专为非重症监护环境设计的胰岛素输注方案的安全性和有效性。
DOI：
10.4158/ep09055.orr
复制
发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Susanna Y Ku
中科院分区：
文献类型：
--
作者：
R. Vinik;Robert E Jones;R. Pendleton;Susanna Y Ku
客观化
目的：确定在非重症监护病房(ICU)的住院患者中，使用简化的胰岛素输注方案能否安全地实现血糖控制。
方法
我们开发了一种新的静脉胰岛素方案，专门用于非ICU环境。然后，我们收集了使用该方案治疗的第一批30名患者的临床数据。我们的研究重点是安全性和血糖控制。
结果
30名患者使用胰岛素输注方案，总计634小时。3例患者出现单次低血糖发作(血糖水平60 mg/dL)。目标平均血糖水平在9小时内达到150 mg/dL。一旦达到血糖目标，平均葡萄糖浓度和中位数葡萄糖浓度分别为156 mg/dL和140 mg/dL。
结论
在非ICU环境下，使用简单的静脉胰岛素方案可以安全有效地控制患者的血糖水平。
OBJECTIVE
To determine whether glycemic control can be safely achieved with use of a simplified insulin infusion protocol in hospitalized patients who are not in the intensive care unit (ICU).
METHODS
We developed a novel intravenous insulin protocol specifically designed for use in the non-ICU setting. We then collected clinical data on the first 30 patients treated with use of this protocol. Our study focused on safety and glycemic control.
RESULTS
The insulin infusion protocol was used in 30 patients for a total of 634 hours. A single hypoglycemic episode (glucose level <60 mg/dL) occurred in 3 patients. The target mean glucose level of <150 mg/dL was achieved in 9 hours. Once the glucose target had been achieved, the mean and median glucose concentrations were 156 mg/dL and 140 mg/dL, respectively.
CONCLUSION
Use of a simple intravenous insulin protocol can safely and effectively control the blood glucose level in patients in a non-ICU setting.